Clin2
NCT04715984Possibly a fitRecruiting

Testing brain-circuit targets during DBS surgery in Parkinson’s

Parkinson Disease

Part of Brain & nervous system clinical trials.

This study looks at how brain connections involved in movement may relate to thinking and memory problems in Parkinson’s disease. It happens during a deep brain stimulation (DBS) operation, using tests while the surgeon is placing an electrode.

Summary written for real people, not researchers, by Clin2.

Phase
N/A
Enrollment
75 people
Ages
40 years and older
Study type
Interventional

Who can take part

  • You are scheduled for deep brain stimulation (DBS) surgery at Vanderbilt under local anesthesia
  • Your planned DBS electrode path will contact the caudate (a deep brain area)
  • You are age 40 or older
  • You have a diagnosis of Parkinson’s disease
  • You can take part in thinking/response tests during surgery and follow instructions
  • You speak English

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07409207Recruiting
Brain signals and reward in Parkinson's surgery

This study looks at brain activity related to reward during deep brain stimulation (DBS) surgery to help us understand Parkinson's disease better. If you are having DBS surgery, your brain signals during the procedure may help researchers.

Nashville, Tennessee
NCT06671626Enrolling by invitation
Brain recordings during DBS surgery for Parkinson's

This study records brain activity during deep brain stimulation (DBS) surgery for Parkinson's disease to better understand how the brain controls actions. It might help improve future treatments.

Dallas, Texas
NCT06778135Recruiting
Brain cell study in Parkinson's DBS surgery

This trial studies how brain cells in a specific area (the prefrontal cortex) affect thinking and planning in people with Parkinson's disease who are getting deep brain stimulation (DBS) surgery. The goal is to learn more about brain function to improve future treatments.

Aurora, Colorado
NCT05482126Recruiting
Studying brain sensing in advanced Parkinson’s during deep brain stimulation

This study looks at how the brain “filters” sensory information in people with advanced Parkinson’s disease, using brain imaging and deep brain stimulation (DBS) that you may already be getting as routine care. The goal is to better understand what drives Parkinson’s symptoms and how DBS might affect the brain.

Birmingham, Alabama
NCT06169852Recruiting
Brain signal study during DBS surgery for Parkinson's

This study looks at brain signals during awake deep brain stimulation (DBS) surgery for Parkinson's disease. The goal is to learn how these signals can help guide the placement of electrodes to improve treatment.

Birmingham, Alabama
NCT06692920Recruiting
Parkinson's brain signals study during DBS surgery

This study looks at brain signals in people with Parkinson's who are already scheduled for Deep Brain Stimulation (DBS) surgery. The goal is to better understand how certain brain pathways work, which could lead to improved treatments.

Minneapolis, Minnesota

Hear when a new Parkinson Disease trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.