Aspirin and clopidogrel after left heart appendix closure
Treatments studied
Part of Brain & nervous system, Heart & circulation clinical trials.
This trial studies a “double anti-platelet” medicine plan (aspirin plus clopidogrel) after closing the left atrial appendage, a procedure used to reduce stroke risk in some heart rhythm conditions. It aims to find a safer, better medicine strategy for people who cannot take standard blood thinners.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older and can give written consent for the study.
- You are being considered for left atrial appendage closure (LAAC) because your care team believes you need it.
- Your heart team agrees that you have a strong reason you cannot take oral anticoagulant (blood thinner) medicine.
- Your doctor says it is safe for you to take aspirin plus clopidogrel, and your bleeding risk is not considered too high.
- You do not have a known allergic reaction to aspirin and/or clopidogrel, and you do not have certain stomach bleeding or bleeding disorders.
- You can safely do an MRI scan (no certain implanted metal/devices, severe claustrophobia, or similar MRI limits).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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