Clin2
NCT04881240Likely a fitRecruiting

Donor T-cell therapy for CD19-positive leukemia in young patients

Acute Lymphoblastic Leukemia, in RelapseAcute Lymphoblastic Leukemia, RefractoryPediatric ALL

Treatments studied

Part of Blood & lymphatic, Cancer, Immune system & allergy clinical trials.

This study tests a new treatment using donor immune cells (T-cells) that target a protein called CD19 on leukemia cells. It is for children and young adults with CD19-positive leukemia that has come back or not responded to standard treatments.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 1
Enrollment
60 people
Ages
Up to 21 years
Study type
Interventional

Who can take part

  • You must be 21 years old or younger.
  • You must have CD19-positive leukemia that has returned or not responded to standard treatment.
  • You must have tried at least two standard treatments (like chemotherapy).
  • Your heart, kidneys, lungs, and liver must be working adequately.
  • You must not have severe, uncontrolled infections or HIV.
  • If you are a female who can have children, you must not be pregnant or breastfeeding and must agree to use birth control.
  • You must not be receiving certain treatments (like systemic steroids) shortly before the study.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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