Testing brain blood-flow control in recent carotid or MCA narrowing
Part of Brain & nervous system, Heart & circulation clinical trials.
This study tests how well your brain controls its own blood flow (“cerebral autoregulation”) after a recent TIA or ischemic stroke caused by a narrowed carotid or MCA artery. It may help researchers understand why symptoms happen and how to better assess brain circulation after stroke.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 80 years old and can speak/participate in testing
- You recently had a TIA or ischemic stroke in the area supplied by a narrowed artery, started within the last 30 days
- You have narrowing on only one side (unilateral): either the carotid artery (ICA) or the middle brain artery (M1 segment of the MCA)
- Your function before the stroke was high (mRS 0–1), and your stroke severity score is not too high (NIHSS 20 or less)
- You can do ultrasound-type testing (you have adequate bone “windows” on both sides) and you can cooperate while awake
- You have not had (and do not plan) a procedure like stenting/endarterectomy for the blocked artery, and you’re not in another trial within 6 months
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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