Tenecteplase for basilar stroke within an extended time window
Treatments studied
Part of Brain & nervous system, Heart & circulation clinical trials.
This trial tests whether giving a clot-busting medicine (tenecteplase) can help people with a specific type of stroke caused by a basilar artery blockage, even if treatment starts later than usual. It aims to improve brain recovery and function by reopening the blocked artery.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Be an adult (18 or older) with symptoms of a posterior circulation stroke from a basilar artery blockage
- Have symptoms (or worsening/drowsiness/coma) start within 24 hours of when you were last known well
- Have a scan (CT angiography or MR angiography) showing a basilar artery blockage that might be retrievable
- Be able to do daily activities before this stroke: pre-stroke mRS 3 or less (only minor help is okay)
- Have no bleeding in the brain on initial scans (no intracerebral hemorrhage or other major alternative cause)
- Be able to receive contrast imaging and follow local consent rules (and not be in another drug study)
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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This trial tests if a clot-busting drug called Tenecteplase helps people with a severe type of stroke in the back of the brain (basilar artery occlusion) when given 4.5 to 24 hours after symptoms start. Patients will then be moved to a hospital that can remove the clot. The goal is to see if the drug improves recovery.
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