Arginine supplement study for newborns after major gut surgery
Treatments studied
Part of Hormones & metabolism, Women’s health & pregnancy clinical trials.
This study looks at whether giving an amino-acid supplement called arginine to newborns after major bowel surgery can improve the baby’s immune response. It may help doctors understand how to support recovery after conditions like necrotizing enterocolitis or certain birth defects.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Your baby was born very early (under 30 weeks) or full/near-term (over 35 weeks).
- Your baby needs major bowel surgery (like laparotomy) or has necrotizing enterocolitis before leaving the hospital; or, for near-term/full-term babies, surgery is needed within the first 3 days of life.
- For babies with necrotizing enterocolitis, it must be at least Stage II (or higher) based on the study’s classification.
- The study team must believe your baby is likely to survive after surgery based on the immediate condition.
- Your baby must not have a known or suspected inherited metabolism disorder or serious liver dysfunction.
- A parent or legal guardian must be able to give informed consent.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This Phase 3 study tests whether not giving nitric oxide during heart-lung bypass in newborns helps reduce the risk of acute kidney injury. It focuses on newborns having heart surgery for congenital heart disease.
This study looks at blood markers in newborns after major stomach or intestine surgery. It aims to understand recovery and could help improve care for babies with similar conditions.
This Phase 2 trial tests whether replacing the body’s arginine (an amino acid) can improve outcomes for children and young adults hospitalized with COVID-19. It may help the immune response, but you must meet several safety criteria to join.
This trial studies whether an oral medicine called L-citrulline (L-cit) is safe and how it works in very preterm infants. It includes two groups: babies with chronic lung disease (with or without high blood pressure in the lungs) and babies recovering from severe bowel infection (NEC).
This study tests whether taking an arginine-based supplement during pregnancy can help lower the risk of bad pregnancy outcomes. You may be eligible if you are pregnant in the early-to-mid period and meet safety and location requirements.
This trial tests whether giving L-arginine (a natural amino acid) soon after heart surgery can help protect your kidneys. It is for adults who had heart surgery with a heart-lung machine and did not have kidney problems before surgery.
Hear when a new Preterm trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.