Protecting the brain during a heart procedure for atrial fibrillation
Part of Heart & circulation, Mental health clinical trials.
This trial studies a way to help protect the brain during a catheter procedure that closes the left atrial appendage (a small heart pouch) in people with atrial fibrillation. It may help lower the risk of stroke-related brain injury for patients who can’t safely take blood thinners.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older and can sign consent yourself (or through a legal process).
- You have atrial fibrillation (comes and goes or is constant).
- Your stroke risk is high enough (CHA2DS2-VASc score of 2 or more).
- You either cannot take blood thinners safely, or you have a high bleeding risk.
- You must not have certain brain or nervous system conditions like dementia, Parkinson’s, or specific rare brain diseases.
- You must not have major heart/heart-vessel problems that stop the procedure or make MRI/testing unsafe.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study tests a combined approach — a catheter ablation to fix the irregular heartbeat (atrial fibrillation) and a device to close the left atrial appendage — in people who recently had a stroke caused by a clot. The goal is to prevent future strokes and reduce the need for long-term blood thinners.
This Phase 3 trial studies whether it’s safer to avoid long-term blood thinners after a spontaneous brain bleed in people with atrial fibrillation (an irregular heart rhythm). It compares different prevention strategies to lower the risk of stroke or other blood-vessel problems without causing new, serious bleeding.
This trial tests the Zenith system, a device that seals off a heart area called the left atrial appendage to reduce stroke risk in people with atrial fibrillation (AF). You may be eligible if you have AF and a doctor recommends LAA closure, and you can return for follow-up scans and visits.
This trial tests a left atrial appendage closure device for people with atrial fibrillation who need an alternative to long-term blood thinners. It aims to see if the procedure can be done safely with conscious sedation instead of general anesthesia.
This trial compares a simpler procedure to the standard one for closing the left atrial appendage in people with non-valvular atrial fibrillation. The goal is to see which approach works better for preventing strokes while lowering bleeding risks.
This trial tests a new type of catheter ablation (using heat to create scar lines in the heart) for people with persistent atrial fibrillation who have a higher risk of stroke or bleeding. It aims to see if this approach can help prevent strokes and reduce the need for long-term blood thinners.
Hear when a new Atrial fibrillation trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.