CPAP machine for high blood pressure when lying down at night
Part of Brain & nervous system, Heart & circulation clinical trials.
This study tests whether using a CPAP breathing machine at night can lower high blood pressure that happens while you sleep. It targets people with nervous-system problems that affect blood pressure changes when standing.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are age 40 to 80
- You have nervous-system (autonomic) problems, such as pure autonomic failure, multiple system atrophy, or Parkinson disease
- When you stand, your blood pressure drops significantly within 3 minutes due to nervous-system reflex problems
- Your overnight test shows high blood pressure while lying down (nighttime top number 140 or higher)
- You can sign consent and follow the study steps
- You are able to temporarily stop any involved treatment and still safely stand for at least 1 minute
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial looks at whether using CPAP (a breathing device) can help control high blood pressure that happens when you lie down, in people with autonomic failure. It’s designed for safety and effectiveness and may improve symptoms and blood pressure control.
This study checks whether raising the head of the bed lowers blood pressure while you’re lying down in people with autonomic failure. It may help find a simple positioning change to reduce risks from high lying blood pressure.
This study checks how your body’s blood pressure and stress responses change after being exposed to heat overnight. It’s meant for people with autonomic failure (like certain Parkinson-related or nerve-function conditions) who also have high blood pressure while lying down, which may help researchers understand safer ways to manage it.
This trial studies whether CPAP treatment can improve blood pressure in people with obstructive sleep apnea. It aims to find out who benefits most from CPAP in terms of blood pressure control.
This study tests whether using CPAP (a breathing machine) for obstructive sleep apnea can improve blood pressure and heartbeat timing. You’ll have blood pressure checked at the start and again after 6 months, along with a sleep evaluation to confirm eligibility.
This study looks at how to manage high blood pressure specifically during sleep, aiming to lower the risk it can cause over time. It may help you if your blood pressure readings stay high at night even if you’re otherwise able to function normally.
Hear when a new Autonomic Failure trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.