NMES therapy to help prevent ICU muscle weakness
Part of Bones, joints & muscles, Brain & nervous system clinical trials.
This trial tests whether a device that delivers small electrical pulses to muscles can help prevent breathing and muscle weakness in very sick ICU patients. It also looks at changes in blood markers that may relate to muscle weakness and recovery.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must have been admitted to the ICU (Christus) between March 2021 and December 2021
- You must have been put on a breathing machine (invasive ventilator) within the last 24–48 hours
- You must be deeply sedated and not very responsive (Sedation-Agitation Scale 1 or 2)
- You must be at risk for ICU-acquired weakness (for example: on a ventilator, sepsis, high blood sugar, high APACHE II score, steroid use, or inactivity from deep sedation)
- A patient or legally authorized surrogate must be able to provide consent in writing
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests whether adding physical therapy early in the ICU can help people with sepsis regain strength and reduce muscle weakness. It focuses on patients who need a breathing tube for at least a week and have a high level of organ failure.
This trial tests whether low-level electrical pulses to the leg muscles can help prevent weakness in patients who need a breathing tube (ventilator) for more than 48 hours. It aims to see if this treatment helps patients recover faster.
This trial tests whether gentle electrical pulses to the muscles can help people 80 or older who are on a breathing machine in the intensive care unit (ICU). It aims to prevent muscle weakness and speed recovery.
This trial tests whether giving muscle stimulation and amino acids can help patients in the ICU who are on a breathing machine to maintain their muscle protein. The study aims to prevent muscle wasting during critical illness.
This trial tests whether electrical muscle stimulation plus extra protein (protein substitute) can improve muscle health and metabolism in critically ill adults in the ICU. If you’re newly admitted and expected to stay on a breathing machine for several days, it may help you keep more muscle strength during recovery.
This trial tests a wearable device that uses mild electrical pulses to stimulate leg muscles, helping prevent muscle weakness in ICU patients with severe infections. It may help you recover strength faster and avoid long-term disability.
Hear when a new Mechanical Ventilation Complication trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.