Clin2
NCT05565105Possibly a fitNot yet recruiting

Stem cell transplant using donor immune cells for leukemia

Leukemia, Myeloid, AcuteLeukemia, Lymphocytic, Acute

Treatments studied

Part of Blood & lymphatic, Cancer, Immune system & allergy clinical trials.

This Phase 2 study looks at a specific type of stem cell transplant that uses donor stem cells with immune cells removed, to treat certain high-risk leukemias and lymphomas. It aims to reduce relapse risk and improve outcomes in people who may need a transplant but have specific disease features.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 2
Enrollment
100 people
Ages
18 years to 74 years
Study type
Interventional

Who can take part

  • You are 18 to 74 years old
  • You have a specific leukemia or lymphoma type with high-risk features, or a disease situation that can be treated by transplant
  • You can do daily activities at least at a moderate level (Karnofsky score 70% or higher)
  • Your heart, liver, kidneys, and lungs tests must meet the study’s limits (your team will review recent results)
  • You must be able and willing to sign informed consent and join the research
  • You must not be pregnant or breast-feeding

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT05735717Recruiting· Phase 2
T-cell transplant using depleted receptors for blood cancers

This Phase 2 study tests a specialized stem cell transplant that removes certain immune “T-cell” receptors to help treat blood cancers like acute leukemia. It may help your body rebuild a healthier immune system after high-dose treatment.

Minneapolis, Minnesota
NCT03314974Recruiting· Phase 2
Stem cell transplant study for blood cancers

This Phase 2 study tests a strong (myeloablative) stem cell transplant using donor stem cells (allogeneic transplant) for certain blood and bone marrow cancers. The goal is to see how well this approach works and whether it can improve outcomes for people who need transplant-level treatment.

Minneapolis, Minnesota
NCT04195633Recruiting· Phase 2
Haploidentical donor stem cell transplant to treat blood cancers

This Phase 2 trial tests whether a specific stem cell transplant method (from a related “half-matched” donor) plus conditioning chemo and radiation can improve outcomes for several blood cancers. It may help people whose cancer is in remission but still considered high risk, or those who have had limited response after prior treatment.

Seattle, Washington
NCT05805605Recruiting· Phase 2
Low-intensity stem cell transplant with donor cells and blood-protection

This Phase 2 study tests a low-intensity bone marrow/stem cell transplant using a matched donor plus two medicines to help prevent the donor cells from attacking you. It aims to treat certain blood cancers—especially when standard treatment has not fully worked or when you are in remission but at higher risk.

Minneapolis, Minnesota
NCT03970096Recruiting· Phase 2
Reduce graft-versus-host disease after stem cell transplant

This Phase 2 study tests ways to lower the risk of graft-versus-host disease (GVHD), a serious complication after an allogeneic stem cell transplant from a matched donor. It is for people with acute leukemia or MDS who are going to receive intensive conditioning therapy, aiming to improve safety while keeping the transplant effective.

Tampa, Florida
NCT04375631Recruiting· Phase 1
Study of chemo plus donor stem cell transplant for blood cancers

This Phase 1 trial tests a specific chemotherapy plan followed by a reduced-intensity donor stem cell transplant for people with relapsed or treatment-resistant acute myeloid leukemia (AML), certain myelodysplastic syndromes (MDS), or chronic myelomonocytic leukemia (CMML). It may help by using donor stem cells to rebuild the bone marrow after intensive cancer treatment, in people who are not responding well to standard therapies.

Seattle, Washington

Hear when a new Leukemia, Myeloid, Acute trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.