Treatment
Eplerenone clinical trials
We’re tracking 10 recruiting studies that include Eplerenone, each written for real people, not researchers, below.
Recruiting studies
- NCT04450953RecruitingPhase 3
Eplerenone to slow blood vessel damage after kidney transplant
This trial tests whether eplerenone can slow the progression of blood vessel (vasculature) problems in people who have had a kidney transplant. You may be eligible if you are older, stable on your transplant medicines, and have higher peripheral artery blood pressure readings.
Vandœuvre-lès-NancyAges 50 years+ - NCT05198791RecruitingPhase 2
Eplerenone for heart injury without blocked heart arteries
This Phase 2 study tests whether eplerenone can improve outcomes after a heart attack (or similar heart injury) when coronary angiography shows no blocked heart arteries. It focuses on people with added cardiovascular risk factors and evaluates how well the treatment works for heart recovery and strain on the heart.
East Kilbride, LanarkshireAges 18 years+ - NCT03984591Enrolling by invitationPhase 4
Compare spironolactone vs eplerenone for heart failure patients
This study uses Denmark’s heart failure registry to compare two common tablet medicines—spironolactone and eplerenone—for people with symptomatic systolic heart failure. It aims to see which one leads to better health outcomes over time.
CopenhagenAges Any age - NCT05030545RecruitingPhase 4
PET/CT study of spironolactone or eplerenone in primary aldosteronism
This study looks at how primary aldosteronism affects the heart and blood vessels, and whether blocking its hormone signal (with spironolactone or eplerenone) changes those findings on imaging tests. It is small and focuses on people with confirmed or suspected primary aldosteronism who are being followed for heart health.
Boston, MassachusettsAges 18–85 - NCT05593055RecruitingPhase 4
Test a heart and blood-pressure therapy in people with hypertension
This study looks at how mineralocorticoid-related hormone signaling affects small heart blood vessels and how efficiently the heart works in people with high blood pressure. It may help doctors understand which treatments could improve heart function in hypertension.
Boston, MassachusettsAges 18–75 - NCT05797558Recruiting
Medication versus surgery for one-sided adrenal hormone problem
This trial compares two ways to treat unilateral primary aldosteronism: taking mineralocorticoid receptor antagonist (MRA) pills or having minimally invasive surgery. It may help decide which option works best and is safest for people who can choose surgery.
GothenburgAges 18–70 - NCT06556732RecruitingPhase 1
Eplerenone for preventing atrial fibrillation return
This trial is testing whether a medication called eplerenone can help prevent atrial fibrillation (AF) from coming back in people who have structural heart disease and have already had their heart rhythm restored to normal. It may be a good option if you are looking for a way to keep your heart in a normal rhythm.
AsyutAges 20–70 - NCT06749418RecruitingEarly Phase 1
Salt intake and blood vessels after preeclampsia
This study tests how a high-salt diet affects blood vessel function in women who had preeclampsia compared to those who did not. It may help understand why preeclampsia increases heart risks later in life.
Iowa City, IowaAges 18–45 - NCT07029503RecruitingPhase 2
Heart failure and kidney function study
This trial tests a new treatment for people with heart failure and severely reduced kidney function. It aims to see if the treatment can help protect both the heart and kidneys.
StockholmAges 18 years+ - NCT07238400RecruitingPhase 2
Heart medication study for women after preeclampsia
This study tests if a medication called a mineralocorticoid receptor antagonist (MRA) can help improve heart function in women who had preeclampsia and now have high blood pressure and signs of heart thickening.
Boston, MassachusettsAges 18–65
What Eplerenone is being studied for
Conditions with recruiting Eplerenone studies.
Common questions
- Are there clinical trials studying Eplerenone?
- Yes. Clin2 currently lists 10 recruiting studies that include Eplerenone, drawn from the U.S. registry and rewritten for real people so you can see what each is testing and who it's for.
- How do I know if I qualify for a Eplerenone trial?
- Each study lists its own eligibility criteria — rules about condition, age, and prior treatments. On every Clin2 trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Is Eplerenone an approved treatment?
- A drug being studied in a trial may be investigational (still being tested) or already approved and being studied for a new use. Each study page explains what phase it's in. Clin2 does not provide medical advice — talk with your doctor about whether Eplerenone or a specific trial is right for you.
Related treatments
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. A drug appearing here is being studied in a trial and may be investigational. Talk with your doctor about whether a specific treatment or trial is right for you.