Heart tissue grafts to help the heart after surgery
Treatments studied
Part of Heart & circulation clinical trials.
This trial tests whether transplanting tiny heart “micrografts” from the left heart chamber area can improve heart function after cardiac surgery. It is meant for people with weakened heart pumping and heart failure symptoms despite medicine.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You can sign informed consent (agree to the study)
- Your heart pumping strength (LVEF) is between 15% and 40% at screening
- You have heart failure symptoms that fall in NYHA class II, III, or IV
- You must be able to have heart scans (including coronary angiogram if needed and LGE-CMRI)
- You do not have certain major recent events or conditions (like a heart attack in the past 30 days)
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests a new artificial blood vessel for heart bypass surgery. If you need a bypass and meet the health requirements, you may be able to receive this experimental graft.
This study tests a new treatment using donor stem cells injected into the heart during scheduled bypass surgery. The goal is to see if these cells help improve heart function in people with heart failure due to blocked arteries and a weak heart pump.
This study looks at tiny structures inside heart muscle cells (especially “power stations” in the cells) in people with certain types of heart failure who are getting coronary bypass surgery. It may help researchers better understand what changes happen in the heart and how this could guide future care.
This trial tests a lab-grown blood vessel that is designed to be used as an extra bypass graft during heart surgery. It aims to offer a safe alternative for patients who need multiple bypasses, and the new vessel may help improve long-term blood flow.
This trial tests a lab-made blood vessel (called an ATEV) used as a bypass graft during heart surgery. The ATEV is designed for people who don't have enough healthy leg vein for standard bypass grafts, and it may help restore blood flow to the heart more safely.
This trial tests whether placing a special membrane with stem cells on the heart during bypass surgery can help improve heart function in people with a weak heart after a previous heart attack.
Hear when a new Ischemic Heart Disease trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.