Heart tissue grafts to help the heart after surgery
Treatments studied
Part of Heart & circulation clinical trials.
This trial tests whether transplanting tiny heart “micrografts” from the left heart chamber area can improve heart function after cardiac surgery. It is meant for people with weakened heart pumping and heart failure symptoms despite medicine.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You can sign informed consent (agree to the study)
- Your heart pumping strength (LVEF) is between 15% and 40% at screening
- You have heart failure symptoms that fall in NYHA class II, III, or IV
- You must be able to have heart scans (including coronary angiogram if needed and LGE-CMRI)
- You do not have certain major recent events or conditions (like a heart attack in the past 30 days)
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests a new artificial blood vessel for heart bypass surgery. If you need a bypass and meet the health requirements, you may be able to receive this experimental graft.
This trial tests a man-made blood vessel (CTEV) as a new option for bypass grafts in people who need heart bypass surgery. It aims to see if the CTEV is safe and effective for improving blood flow to the heart.
This study looks at tiny structures inside heart muscle cells (especially “power stations” in the cells) in people with certain types of heart failure who are getting coronary bypass surgery. It may help researchers better understand what changes happen in the heart and how this could guide future care.
This trial tests a new device called the VentriCure that helps the heart pump blood. It is for people with severe coronary artery disease and a weak heart who cannot have bypass surgery or choose not to.
This trial tests a patch made from lab-grown heart muscle cells that is placed on the heart during bypass surgery. It aims to see if the patch can improve heart function in people with severe heart failure.
This early-phase study tests a lab-made heart tissue (“engineered myocardium”) placed surgically to help the heart work better in people with advanced heart failure. It mainly checks safety first, and also looks for signs the patch can improve heart function in selected patients.
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