Clin2
NCT07710066Possibly a fitNot yet recruiting

Studying waking up from sedation in intensive care patients

Critical IllnessMechanical VentilationWeaning Invasive Mechanical VentilationSedation and AnalgesiaCritical Care MedicineDelirium

Part of Brain & nervous system, Mental health clinical trials.

This study looks at how patients in the intensive care unit wake up from sedation and pain medication after being on a breathing machine. The goal is to understand how the medications affect recovery and to improve how they are stopped.

Summary written for real people, not researchers, by Clin2.

Phase
N/A
Enrollment
500 people
Ages
18 years and older
Study type
Observational

Who can take part

  • You are 18 years old or older.
  • You are in the intensive care unit (ICU) on a breathing machine for at least 24 hours.
  • You have been given continuous sedative and pain medications.
  • You are not on a heart-lung support machine (ECMO).
  • You do not have a primary brain injury like a severe head injury, stroke, or brain infection.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT06203405Recruiting
Sedation guided by breathing effort in ICU patients

This trial tests a new way to manage sedation (medication to keep you calm and comfortable) for people on a breathing machine. The goal is to see if adjusting sedation based on your breathing effort leads to better outcomes and shorter time on the machine.

Bangkok, Bangkok
NCT07350122Not yet recruiting
Monitoring sedation after heart surgery in the intensive care unit

This study compares different ways of monitoring how deeply sedated patients are while on a breathing machine after heart surgery. It aims to find the best approach to keep you comfortable and safe in the intensive care unit.

NCT07032987Recruiting
Improving sedation with a new care plan for ICU patients

This trial tests a new sedation protocol for adults in intensive care who need strong pain relief or sedation medicines. It aims to make sedation safer and more comfortable, and includes people on ECMO (a heart-lung machine) or a ventilator (breathing machine) for severe breathing problems.

London, London
NCT05751863Recruiting
Sedation-first vs usual care in ventilated trauma patients

This study compares how pain medicine and calming medicine are started in critically injured (trauma) adults who are on a breathing machine. It aims to see whether a specific “analgesia-first” approach can improve comfort and support breathing weaning.

Long Beach, California
NCT07590687Not yet recruiting· Phase 3
Ketamine for faster recovery after breathing tube removal

This trial tests if adding ketamine to standard sedation helps people wake up faster and recover better after being on a breathing machine. It may reduce confusion and improve outcomes for critically ill patients.

Paris
NCT06718764Recruiting
Bedside brain monitor study for sedated ICU patients

This study tests a new bedside monitoring system that tracks brain activity in ICU patients who are on a breathing machine and receiving sedative medications. It aims to help doctors better manage sedation and improve patient care.

New York, New York

Hear when a new Critical Illness trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.