Clin2
NCT05762107Possibly a fitRecruiting

Drug ZT-01 to reduce low blood sugar at night

Type 1 Diabetes Mellitus With Hypoglycemia

Treatments studied

Part of Hormones & metabolism clinical trials.

This Phase 2 study tests ZT-01 to help prevent night-time low blood sugar (hypoglycemia) in people with type 1 diabetes. It may help if you’ve had low blood sugar during sleep or are at high risk based on recent glucose monitoring.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 2
Enrollment
186 people
Ages
18 years to 75 years
Study type
Interventional

Who can take part

  • Have type 1 diabetes for at least 5 years
  • Be at risk for night-time low blood sugar based on recent CGM data or recent screening checks
  • Have an HbA1c of 10.0% or less (a longer-term blood sugar measure)
  • Have a BMI between 18.5 and under 33
  • In the last 4 weeks, have not had 1 or more severe lows needing help (and in the last 3 months, not 2 or more)

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07797335Recruiting· Phase 3
Zenagamtide for diabetes and weight loss

This study compares a new once-weekly injection to lower blood sugar levels against a standard daily injection in people with type 2 diabetes who are at high risk for heart problems. It aims to find out if the new medicine is more effective in managing blood sugar and body weight.

Birmingham, Alabama
NCT06847178Not yet recruiting· Phase 2/Phase 3
Study of LC-Z300-01 for adults with type 2 diabetes

This study tests a new medicine called LC-Z300-01 to see if it is safe and works well for people with type 2 diabetes. It may help lower blood sugar levels.

Shanghai, Shanghai Municipality
NCT07387003Not yet recruiting· Phase 2
Study of GZR101-80 for type 2 diabetes

This study tests an investigational medicine called GZR101-80 for people with type 2 diabetes. It aims to see how well it controls blood sugar and how safe it is.

Beijing
NCT05626712Recruiting· Phase 1/Phase 2
CELZ-201 to preserve insulin production in early type 1 diabetes

This Phase 1/2 study tests whether CELZ-201 is safe and can help the body keep making some of its own insulin in people who were recently diagnosed with type 1 diabetes. You may be eligible if your diabetes started within the past year and your tests show you still have some insulin-making activity.

Miami, Florida
NCT07550816Recruiting· Phase 1
Safety study of ZT002 injection in overweight adults

This study tests how a new diabetes medicine called ZT002 works in the body and whether it interacts safely with other common medications. Researchers will monitor healthy volunteers who are overweight to understand the medicine's safety and effectiveness.

Chengdu, Sichuan
NCT06829563Recruiting· Phase 1
Testing safety of new diabetes drug RZ-629

This early-phase study tests a new medicine called RZ-629. It looks at how safe it is, how the body processes it, and how it works in both healthy people and people with type 2 diabetes. If you have diabetes, you can join if your blood sugar is well controlled on your current pills.

Adelaide

Hear when a new Type 1 Diabetes Mellitus With Hypoglycemia trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.