Drug ZT-01 to reduce low blood sugar at night
Treatments studied
Part of Hormones & metabolism clinical trials.
This Phase 2 study tests ZT-01 to help prevent night-time low blood sugar (hypoglycemia) in people with type 1 diabetes. It may help if you’ve had low blood sugar during sleep or are at high risk based on recent glucose monitoring.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Have type 1 diabetes for at least 5 years
- Be at risk for night-time low blood sugar based on recent CGM data or recent screening checks
- Have an HbA1c of 10.0% or less (a longer-term blood sugar measure)
- Have a BMI between 18.5 and under 33
- In the last 4 weeks, have not had 1 or more severe lows needing help (and in the last 3 months, not 2 or more)
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study tests a new once-daily injection (LC-Z300-01) to see if it can lower blood sugar safely in people with type 2 diabetes. It may be a good option if your current diabetes medications aren't controlling your blood sugar as well as you'd like.
This Phase 1/2 study tests whether CELZ-201 is safe and can help the body keep making some of its own insulin in people who were recently diagnosed with type 1 diabetes. You may be eligible if your diabetes started within the past year and your tests show you still have some insulin-making activity.
This study tests how a new diabetes medicine called ZT002 works in the body and whether it interacts safely with other common medications. Researchers will monitor healthy volunteers who are overweight to understand the medicine's safety and effectiveness.
This early-phase study tests a new medicine called RZ-629. It looks at how safe it is, how the body processes it, and how it works in both healthy people and people with type 2 diabetes. If you have diabetes, you can join if your blood sugar is well controlled on your current pills.
This trial tests an experimental insulin (GZR101-80) to see if it helps control blood sugar in people with type 2 diabetes. You may join if you’ve had type 2 diabetes for at least 6 months and are between 18 and 75 years old.
This study is looking for adults with type 1 diabetes to help improve guidelines for preventing and treating low blood sugar (hypoglycemia). The goal is to make recommendations that are more practical and safer for people like you.
Hear when a new Type 1 Diabetes Mellitus With Hypoglycemia trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.