Testing cooling treatment after lack of oxygen at birth
Part of Brain & nervous system, Heart & circulation clinical trials.
This trial studies outcomes in newborns who had breathing problems from low oxygen before or during birth and were treated with a cooling therapy (therapeutic hypothermia). It may help doctors understand which babies benefit most and what recovery looks like over time.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Your baby was born at 35 weeks or later and weighs at least 1,800 g (about 4 lb).
- The delivery or first hour suggests low oxygen or stress (for example, very low blood pH, very abnormal blood gas, very low Apgar score, or needing breathing support at 10 minutes).
- The baby shows moderate or severe brain illness signs in the first 30–60 minutes after birth (for example, very sleepy with weak movement, or stupor/coma).
- An EEG or brain-wiring test (aEEG/EEG) at first may show concerning patterns for at least 30 minutes, or the baby has seizures.
- Doctors must be able to start the cooling treatment within 6 hours of birth, and you must give consent.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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