Ablation vs best medicines for CRT patients with permanent atrial fibrillation
Part of Heart & circulation clinical trials.
This trial compares two approaches—an AV junction ablation procedure versus continued best medical treatment—in people who already have a heart device for heart failure (CRT) but still have ongoing permanent atrial fibrillation. It aims to improve how well your heart rhythm is controlled and how effectively the device can pace your heart.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have had a CRT device (biventricular pacemaker/defibrillator or a conduction system pacemaker) for more than 6 months
- You have atrial fibrillation that is permanent or keeps coming back as persistent, with at least one recent emergency visit or hospital stay in the past year
- You are already on the best available medicines for heart failure and rate control, as decided by your care team
- Your device readings show pacing effectiveness with BiVP% + VPC% between 85% and under 99% after at least 1 month on optimized treatment
- You are between 18 and 84 years old and can sign the informed consent
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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