Nitric oxide breathing gas for children with lung failure
Part of Lungs & breathing clinical trials.
This trial tests whether adding a breathing gas called nitric oxide to standard care helps children with severe lung failure (ARDS) recover faster. It is for children on a breathing machine who still have low oxygen levels.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Your child is older than 37 weeks corrected age and up to 21 years old (including adults who cannot consent).
- Your child has been on a breathing machine for less than 72 hours and has severe lung failure (ARDS) with low oxygen levels.
- Your child is not currently on a special breathing machine called high-frequency ventilation or a heart-lung machine (ECMO), and is not already receiving nitric oxide.
- Your child does not have a significant air leak from their breathing tube or chest tube (more than 20%).
- Your child does not have a blue-type heart defect (cyanotic congenital heart disease) or a do-not-resuscitate order.
- Your child has had a blood gas test done before starting any special treatments.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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