Breathing nitric oxide during clot-removal for stroke
Part of Brain & nervous system, Heart & circulation clinical trials.
This Phase 1 study tests whether inhaled nitric oxide (a gas breathed through a ventilator) can improve outcomes in people having a specific kind of emergency stroke procedure to remove a clot from the brain. It focuses on patients who need general anesthesia for the clot-removal procedure and have imaging results that suggest salvageable brain tissue.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Be 18 to under 80 years old
- Have an acute non-bleeding ischemic stroke confirmed by tests, with NIH Stroke Scale score 6 or higher
- Start of stroke symptoms must be within 16 hours before the clot-removal procedure begins
- Plan for the clot-removal (mechanical thrombectomy) to use general anesthesia and a ventilator
- CT scan and other brain imaging must show the right pattern (a minimum score on head CT, and enough “at-risk” brain tissue on CT perfusion)
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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