Inhaled nitric oxide for moderate to severe COPD symptoms
Treatments studied
Part of Lungs & breathing clinical trials.
This study tests whether inhaled nitric oxide gas can improve outcomes in people with moderate-to-severe chronic obstructive pulmonary disease (COPD). It may help reduce breathing problems by targeting how airways and blood vessels respond in the lungs.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Be between 40 and 75 years old
- Have a past smoking history of at least 10 pack-years and stopped smoking at least 1 month ago
- Have COPD confirmed by breathing tests: low airflow after using a bronchodilator (FEV1/FVC < 0.7 and FEV1 30% to 80% of predicted)
- Be able to sign consent and complete all required study visits and tests
- Not be pregnant or breastfeeding
- Not have had a COPD flare in the last month that required starting or increasing steroid pills
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests whether breathing in nitric oxide gas can improve how well your lungs exchange oxygen and carbon dioxide. It may help people with mild or moderate COPD, and also includes healthy volunteers for comparison.
This Phase 2 trial tests whether sildenafil tablets can improve exercise ability, shortness of breath, and heart-lung function in people with COPD. It also compares against people without COPD to better understand how sildenafil affects breathing tests.
This trial tests whether a gas called nitric oxide, breathed in through the nose or mouth, can help people with moderate to severe COPD. It could improve breathing and quality of life.
This trial tests whether inhaled nitric oxide can help people with severe obesity who are on a breathing machine because their lungs aren't getting enough oxygen. It aims to see if this treatment improves oxygen levels and recovery.
This study tests whether giving inhaled nitric oxide gas helps improve lung function in patients on a breathing tube with mild to moderate acute lung injury (ARDS). Participants will receive standard care plus the study gas, and the team will use special imaging to see how the lungs respond.
This study tests whether breathing in a special gas called nitric oxide can help people with moderate to severe ARDS (a severe form of lung failure that makes it hard to breathe). The gas is used to improve oxygen levels and may help patients on a ventilator recover.
Hear when a new Chronic Obstructive Pulmonary Disease trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.