Treatment
Inhaled Nitric Oxide clinical trials
We’re tracking 18 recruiting studies that include Inhaled Nitric Oxide, each written for real people, not researchers, below.
Recruiting studies
- NCT05801224Recruiting
Vascular ARDS recruitment after inhaled nitric oxide
This study tests whether giving nitric oxide gas through a breathing tube helps people with a lung condition called ARDS (acute respiratory distress syndrome) recover and leave the intensive care unit sooner. It may help some patients with mild-to-moderate cases who need a ventilator and a central line.
Boston, MassachusettsAges 18–80 - NCT06741137Recruiting
Inhaled nitric oxide and prone positioning for ARDS
This trial is testing whether adding inhaled nitric oxide to lying on your stomach (prone position) can help people with severe lung failure (ARDS) who are on a ventilator. It uses a special monitor (EIT) to check lung function in real time.
Yangzhou, JiangsuAges 18–80 - NCT06852924Recruiting
Inhaled nitric oxide for HAPE treatment trial
This trial tests if inhaled nitric oxide helps people with high-altitude pulmonary edema (fluid in the lungs from high altitude). It may offer a new treatment option for those with mild to moderate symptoms.
Lhasa, TibetAges 18–65 - NCT05213676RecruitingPhase 4
Testing stopping inhaled nitric oxide in newborns with CDH
This trial studies whether stopping inhaled nitric oxide (a breathing medicine) can be safely used in newborns with congenital diaphragmatic hernia (CDH). It may help the team decide the best way to use this medicine during early newborn care.
Birmingham, AlabamaAges birth–1 month - NCT05896800Recruiting
Inhaled nitric oxide for moderate to severe COPD symptoms
This study tests whether inhaled nitric oxide gas can improve outcomes in people with moderate-to-severe chronic obstructive pulmonary disease (COPD). It may help reduce breathing problems by targeting how airways and blood vessels respond in the lungs.
Nanjing, JiangsuAges 40–75 - NCT06832163Recruiting
Smart weaning from inhaled nitric oxide for newborns with PPHN
This trial tests a new, smart way to slowly reduce (wean) the inhaled nitric oxide gas that helps babies with a serious lung condition called PPHN. If your baby is already responding well to iNO and needs it for at least 24 hours, this study might help make the weaning process safer and more effective.
ShanghaiAges Any age - NCT07099144Recruiting
Inhaled nitric oxide for newborns with breathing failure and high blood pressure in the lungs
This trial tests whether inhaled nitric oxide gas can help full-term newborns who have severe breathing problems and high blood pressure in their lungs. It aims to improve oxygen levels and reduce the need for more intensive support.
Guangzhou, GuangdongAges Up to 1 week - NCT07382258Recruiting
Inhaled nitric oxide for COPD: a clinical study
This trial tests whether a gas called nitric oxide, breathed in through the nose or mouth, can help people with moderate to severe COPD. It could improve breathing and quality of life.
Nanjing, JiangsuAges 40–75 - NCT05616910Enrolling by invitationPhase 2
Inhaled nitric oxide for microvascular problems after brain injury
This Phase 2 study tests whether inhaled nitric oxide can improve tiny blood-flow problems in the brain after traumatic brain injury. If you qualify, you may receive inhaled nitric oxide and be monitored for safety and recovery.
Philadelphia, PennsylvaniaAges 18–75 - NCT06702553RecruitingPhase 3
Nitric oxide to reduce support after heart surgery
This trial tests whether giving nitric oxide gas during heart surgery can help patients recover faster and need less breathing and circulation support afterward. It is for people having planned heart or aortic surgery with a heart-lung machine for the first time.
Boston, MassachusettsAges 18 years+ - NCT05871606RecruitingPhase 1
Breathing nitric oxide during clot-removal for stroke
This Phase 1 study tests whether inhaled nitric oxide (a gas breathed through a ventilator) can improve outcomes in people having a specific kind of emergency stroke procedure to remove a clot from the brain. It focuses on patients who need general anesthesia for the clot-removal procedure and have imaging results that suggest salvageable brain tissue.
Charlotte, North CarolinaAges 18–80 - NCT06690801Recruiting
Nitric oxide breathing gas for children with lung failure
This trial tests whether adding a breathing gas called nitric oxide to standard care helps children with severe lung failure (ARDS) recover faster. It is for children on a breathing machine who still have low oxygen levels.
Los Angeles, CaliforniaAges birth–21 years - NCT06950294RecruitingEarly Phase 1
Inhaled nitric oxide for pneumonia patients on a ventilator
This study tests an inhaled gas (iNO300) given through your breathing tube to improve oxygen levels in critically ill patients with pneumonia. You may qualify if you are on a ventilator and have been diagnosed with pneumonia within the last 3 days.
Boston, MassachusettsAges 18 years+ - NCT06164639Enrolling by invitation
Biomarkers and causes of lung injury from reflux
This study looks at why some people on breathing tubes develop lung damage from stomach acid getting into the lungs. It may help find better ways to prevent or treat this injury.
ShanghaiAges 18–99 - NCT05703191Recruiting
Tests an inhaled nitric oxide system for newborn lung pressure
This study looks at whether an inhaled nitric oxide generator and delivery system can help newborns with high lung blood pressure (pulmonary hypertension). It may help improve oxygen levels during breathing support, but it requires specific medical eligibility and informed consent.
Guangzhou, GuangzhouAges Any age - NCT05101746Enrolling by invitationPhase 2/Phase 3
Nitric oxide to protect brain and kidneys in babies during heart surgery
This trial studies whether giving nitric oxide during heart-lung bypass surgery can help protect a baby’s brain and kidneys. If you qualify, the study team will check outcomes after surgery to see if benefits happen compared with usual care.
Nashville, TennesseeAges birth–1 year - NCT04216927RecruitingPhase 3
Neonates on heart-lung bypass get NO to prevent kidney injury
This Phase 3 study tests whether not giving nitric oxide during heart-lung bypass in newborns helps reduce the risk of acute kidney injury. It focuses on newborns having heart surgery for congenital heart disease.
Cincinnati, OhioAges 1 day–1 month - NCT05985330Recruiting
Study of FeNO as a marker for immunotherapy response in lung cancer
This trial is testing whether a simple breath test (FeNO) can predict how well immunotherapy works in people with advanced lung cancer who haven't had treatment before. It's for patients whose tumors have high PD-L1 levels and who will receive immunotherapy alone.
DijonAges 18 years+
What Inhaled Nitric Oxide is being studied for
Conditions with recruiting Inhaled Nitric Oxide studies.
Common questions
- Are there clinical trials studying Inhaled Nitric Oxide?
- Yes. Clin2 currently lists 18 recruiting studies that include Inhaled Nitric Oxide, drawn from the U.S. registry and rewritten for real people so you can see what each is testing and who it's for.
- How do I know if I qualify for a Inhaled Nitric Oxide trial?
- Each study lists its own eligibility criteria — rules about condition, age, and prior treatments. On every Clin2 trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Is Inhaled Nitric Oxide an approved treatment?
- A drug being studied in a trial may be investigational (still being tested) or already approved and being studied for a new use. Each study page explains what phase it's in. Clin2 does not provide medical advice — talk with your doctor about whether Inhaled Nitric Oxide or a specific trial is right for you.
Related treatments
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. A drug appearing here is being studied in a trial and may be investigational. Talk with your doctor about whether a specific treatment or trial is right for you.