Tenecteplase for stroke 4.5 to 6 hours after onset
Treatments studied
Part of Brain & nervous system, Heart & circulation clinical trials.
This trial tests a medicine called tenecteplase (a clot-buster) for people who have a moderate or severe stroke caused by a clot and can be treated 4.5 to 6 hours after symptoms start. It aims to see if this medicine can help improve recovery.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 or older.
- You had a stroke caused by a blood clot, not a bleed.
- Your stroke symptoms started between 4.5 and 6 hours ago.
- Your stroke symptoms are moderate to severe (NIHSS score 4 or higher).
- You have not had a major disability before this stroke.
- You do not have any conditions that make blood-thinning medicine dangerous (like recent bleeding, surgery, or high blood pressure).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests a clot-busting drug called tenecteplase for people who had a stroke in the back of the brain and arrive at the hospital within 4.5 to 24 hours of symptoms. It aims to see if giving this drug later than usual can improve recovery and reduce disability.
This study tests a medication called tenecteplase, given before a procedure to remove a large blood clot in the brain. It may help people who have had a severe stroke within the last 4.5 hours.
This trial tests if giving a second dose of a clot-busting drug (tenecteplase) helps people who had a stroke and didn't improve much after the first dose. You must receive the second dose within 4.5 hours of your stroke symptoms starting.
This trial tests whether giving a clot-busting medication (tenecteplase) directly into the artery after an incomplete clot-removal procedure can improve blood flow and outcomes in people with large vessel strokes. It aims to help those who had partial reopening after mechanical thrombectomy.
This trial tests a clot-dissolving medicine called tenecteplase for people who had a stroke more than 4.5 hours ago. It may help you recover if given later than usual.
This trial tests if the clot-busting drug tenecteplase can help people with a moderate to severe stroke when given 24 to 72 hours after symptoms began. It aims to see if this later treatment window can improve recovery and reduce disability.
Hear when a new Stroke, Ischemic trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.