Clin2
NCT07083154Possibly a fitRecruiting

Mazdutide for type 2 diabetes with early memory problems

Dementia, MildMild Cognitive ImpairmentType 2 Diabetes

Treatments studied

Part of Blood & lymphatic, Brain & nervous system, Cancer, Hormones & metabolism, Immune system & allergy, Mental health clinical trials.

This study tests a new medication, Mazdutide, to see if it can slow or improve memory and thinking problems in people with type 2 diabetes and early-stage cognitive impairment. It may help by targeting blood sugar control and possibly reducing the impact of diabetes on brain function.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 3
Enrollment
420 people
Ages
50 years to 75 years
Study type
Interventional

Who can take part

  • You have type 2 diabetes and your blood sugar (HbA1c) is between 7.0 and 9.0%.
  • You are between 50 and 75 years old.
  • You have mild memory or thinking problems (either mild cognitive impairment or mild dementia) that have been worsening slowly for at least 6 months.
  • Your diabetes treatment has been stable for the last 3 months (can be diet-only or with metformin, sulfonylureas, etc., possibly plus a long-acting bedtime insulin).
  • You have a body mass index (BMI) of 20 or higher and your weight has been stable for 3 months.
  • You are willing to undergo cognitive tests, MRI scans, and follow the study protocol.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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