Study of cholesterol-lowering drug in people having aneurysm surgery
Treatments studied
Part of Heart & circulation clinical trials.
This trial tests whether a drug that lowers cholesterol (a PCSK9 inhibitor) can help patients preparing for aneurysm surgery. It will examine how the drug affects the aneurysm tissue during surgery, which may guide future treatment.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have an abdominal aortic aneurysm that needs open surgery to fix it.
- You are older than 18 years.
- You have not taken a PCSK9 inhibitor (evolocumab, alirocumab, or inclisiran) in the last 6 months.
- Your LDL cholesterol is not very low (below 40 mg/dL) in the last 3 months.
- You do not have poorly controlled diabetes (A1C above 10%), severe kidney disease, or significant liver disease.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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