Lemborexant for insomnia in dementia: a personalized trial
Treatments studied
Part of Brain & nervous system, Hormones & metabolism, Mental health clinical trials.
This trial tests if the sleep medication lemborexant can help people with early-stage dementia who also have insomnia. It uses an N-of-1 design, meaning it will look at how you personally respond to the drug compared to a placebo.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Diagnosed with early-stage dementia
- Bothersome insomnia that affects your sleep
- No other sleep disorders that would make this medication unsafe
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study tests if lemborexant, a sleep medication, can help people with both a mental health condition and insomnia. You would take the medicine as prescribed and complete questionnaires over 2 months.
This trial tests whether a medication that blocks brain chemicals involved in wakefulness can help reduce markers of nerve damage in people with insomnia. It is for adults aged 40–65 with chronic insomnia, and it aims to see if improving sleep may protect brain health.
This trial tests a sleep medication called lemborexant in people with Parkinson's disease who also have insomnia. The goal is to see if it improves both sleep and movement symptoms.
This study tests if the sleep medication lemborexant can help people with opioid use disorder who also have chronic insomnia. Participants must already be taking buprenorphine (Suboxone) for at least 4 weeks. The goal is to see if better sleep improves mood and reduces opioid use.
This trial tests whether a part of the brain called the locus coeruleus is involved in insomnia. It involves sleep questionnaires and possibly brain imaging to understand your sleep problems better.
This study follows adults with insomnia who are prescribed a new sleep medication called daridorexant. It aims to see how well the medication works in a real-world setting, and to monitor its safety and effects on sleep.
Hear when a new Insomnia trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.