Study of a new drug for advanced prostate cancer
Treatments studied
Part of Cancer, Kidney & urinary clinical trials.
This study tests a new oral drug called opevesostat against another standard hormone therapy for men with advanced prostate cancer that has spread and is no longer controlled by a first hormone therapy. It's for men who have not had chemotherapy for this stage and who have not used a PARP inhibitor or chose not to.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have been diagnosed with prostate cancer that has spread to other parts of the body (like bones or lymph nodes).
- Your cancer got worse while on a next-generation hormone therapy (like abiraterone, enzalutamide, darolutamide, or apalutamide).
- You have not had chemotherapy for castration-resistant prostate cancer that has spread.
- You have either tried a PARP inhibitor, were told you cannot take one, or chose not to.
- You are still on hormone therapy (ADT) or have had your testicles removed, and your testosterone level is low enough.
- You are generally in good health (able to do your daily activities) and your organs are working well.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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