Spironolactone for maintaining normal heart rhythm in atrial fibrillation
Treatments studied
Part of Heart & circulation clinical trials.
This study tests whether the drug spironolactone can help keep your heart in a normal rhythm after episodes of atrial fibrillation. It's for people with high blood pressure and a type of atrial fibrillation that comes and goes.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 or older.
- You have high blood pressure that's been treated with medication for at least a year.
- You have atrial fibrillation (irregular heartbeat) that is not constant or has not lasted continuously for more than a year.
- You are in a normal heart rhythm (sinus rhythm) at the start of the study.
- You are not pregnant, breastfeeding, or planning to become pregnant during the study.
- You do not have severe kidney or liver problems, or other conditions that would prevent taking spironolactone.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study tests whether eplerenone (a pill that helps control heart rhythm) can prevent atrial fibrillation from coming back in people with structural heart disease. You may qualify if your AF is the coming-and-going type and you've already been returned to a normal rhythm.
This trial is testing whether a medication called eplerenone can help prevent atrial fibrillation (AF) from coming back in people who have structural heart disease and have already had their heart rhythm restored to normal. It may be a good option if you are looking for a way to keep your heart in a normal rhythm.
This study tests a stepwise treatment plan for people with persistent atrial fibrillation (a long-lasting irregular heartbeat) who also have an enlarged left atrium. It aims to see if a medication called amiodarone plus a cardioversion procedure can help restore normal rhythm.
This trial tests whether starting spironolactone helps people with heart failure symptoms when the heart pumps “preserved” (not severely reduced). Participants are assigned to start spironolactone or usual care so researchers can see if it improves outcomes.
This trial tests whether chloroquine can reduce symptoms in people with persistent atrial fibrillation (AF), an irregular heartbeat that lasts longer than a week. It will also closely monitor heart rhythm and safety, since the medicine can affect the heart and other organs.
This trial tests whether a target heart rate (below 80 beats per minute) is better than a more lenient one for people with persistent or permanent atrial fibrillation. It aims to find the best way to control your heart rate and improve your quality of life.
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