Nitroglycerin plus radiation for EGFR-mutant lung cancer with brain spread
Treatments studied
Part of Brain & nervous system, Cancer, Lungs & breathing clinical trials.
This trial tests whether adding nitroglycerin (a medicine that widens blood vessels) to standard whole-brain radiation helps improve treatment for lung cancer that has spread to the brain. It is for people with a specific gene change (EGFR mutation) in their cancer.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have advanced non-small cell lung cancer that has spread to your brain
- Your tumor has an EGFR mutation (a specific gene change)
- You are able to receive whole-brain radiation therapy
- You are 18 years or older, and your general health is fairly good (ECOG score 0-2)
- You are not taking certain heart medications like calcium channel blockers or nitrates
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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