Comparing two medications for acute heart failure with fluid buildup
Treatments studied
Part of Heart & circulation clinical trials.
This trial tests if dapagliflozin or acetazolamide works better for people hospitalized with heart failure who have extra fluid in their body (congestion). The study will compare how well each medication helps remove fluid when used with standard IV diuretics.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older.
- You are hospitalized for acute heart failure with signs of fluid overload (like swelling in legs, trouble breathing when lying flat, or extra fluid seen on chest X-ray).
- Treatment starts within 24 hours of being in the hospital.
- You will be receiving IV diuretics (water pills) during this hospital stay.
- Your kidney function is good enough (eGFR at least 30, which means kidneys are working at about 30% or more of normal).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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