Treatment
Acetazolamide clinical trials
We’re tracking 25 recruiting studies that include Acetazolamide, each written for real people, not researchers, below.
Recruiting studies
- NCT07635563RecruitingPhase 2
Sleep Apnea Treatment with Dronabinol and Acetazolamide
This study tests a combination medication (dronabinol and acetazolamide) to treat obstructive sleep apnea in people who cannot tolerate or use CPAP machines. The goal is to find the right dose that safely reduces breathing interruptions during sleep.
Chula Vista, CaliforniaAges 18–65 - NCT06783166RecruitingPhase 2/Phase 3
Comparing two medications for acute heart failure with fluid buildup
This trial tests if dapagliflozin or acetazolamide works better for people hospitalized with heart failure who have extra fluid in their body (congestion). The study will compare how well each medication helps remove fluid when used with standard IV diuretics.
Al MansurahAges 18 years+ - NCT06475105RecruitingPhase 4
Acetazolamide and Furosemide for Acute Heart Failure
This trial tests whether adding an oral water pill (acetazolamide) to standard IV furosemide helps people with acute heart failure who have fluid overload. It aims to see if the combination improves outcomes better than furosemide alone.
Semarang, Central JavaAges 18 years+ - NCT05802849RecruitingPhase 4
Oral acetazolamide for worsening heart failure
This trial tests whether taking acetazolamide by mouth can help prevent or improve worsening (decompensation) of heart failure after you needed IV water pills (diuretics). It’s mainly for adults with a recent heart-failure flare and specific heart/lab signs, while carefully excluding certain low blood pressure, kidney issues, and electrolyte or acid–base problems.
SamaraAges 18 years+ - NCT06535529RecruitingPhase 3
Comparing Two Water Pills for Worsening Heart Failure
This study compares two medicines—acetazolamide and dapagliflozin—to see which works better at removing extra fluid in people hospitalized for worsening heart failure. It may help decide the best treatment for fluid overload.
CairoAges 18 years+ - NCT06091085RecruitingPhase 1/Phase 2
Acetazolamide for sleep apnea in untreated patients
This study tests a medicine called acetazolamide to see if it can improve how your brain controls breathing during sleep apnea. If you have sleep apnea and are not using treatment, you might be able to join.
Boston, MassachusettsAges 21–80 - NCT03467360RecruitingPhase 1
Adding an acetazolamide-type drug to lung cancer radiation and drugs
This Phase 1 trial tests whether blocking an enzyme (with an acetazolamide-like medicine) can be safely combined with standard treatment for small cell lung cancer that has not spread. The goal is to see if the treatment can be given safely and to learn early signs of benefit.
NiceAges 18 years+ - NCT05804084RecruitingPhase 2
Acetazolamide for sleep apnea: sleep and brain outcomes
This study tests acetazolamide (a medicine that changes breathing chemistry) to see how it affects sleep quality and neurocognitive (brain/memory/attention) outcomes in adults with untreated moderate to severe sleep apnea. You may be eligible if you have significant sleep apnea but do not have certain safety risks or need to start standard sleep apnea treatment right away.
La Jolla, CaliforniaAges 18 years+ - NCT06285760Recruiting
Acetazolamide for fluid removal in acute heart failure
This study tests whether adding acetazolamide (a different type of water pill) to your current treatment helps remove extra fluid from your body more effectively when you are in the hospital for heart failure.
MadridAges Any age - NCT06521476RecruitingPhase 2
Acetazolamide for sleep apnea in people on opioid treatment
This trial tests if a drug called acetazolamide can help people with central sleep apnea who are also on medication for opioid use disorder. Sleep apnea causes breathing to stop during sleep, and this study aims to see if the drug improves their sleep breathing.
Pittsburgh, PennsylvaniaAges 18–100 - NCT04887792RecruitingPhase 1/Phase 2
Acetazolamide for schizophrenia that hasn’t improved
This Phase 1/2 study tests whether acetazolamide can help people with treatment-resistant schizophrenia. It aims to see if adding this medication improves symptoms when standard antipsychotics haven’t worked enough.
Pittsburgh, PennsylvaniaAges 18–55 - NCT06945848Recruiting
Stenting for Intracranial Hypertension on Acetazolamide
This trial tests whether placing a stent (a small tube) in a narrowed brain vein can help reduce pressure in the head in people with Intracranial Hypertension who have been on acetazolamide for over a year. It may be an option if you still have high pressure despite medication.
MontpellierAges 18 years+ - NCT06981234RecruitingPhase 2
Acetazolamide for type 1 diabetes
This trial tests whether a medicine called acetazolamide (used for altitude sickness) can help people with type 1 diabetes. It compares how your body responds while on the drug versus a placebo, using a crossover design so everyone gets both treatments.
La Jolla, CaliforniaAges 18 years+ - NCT07101250RecruitingPhase 4
Study of acetazolamide before laparoscopic hysterectomy
This trial tests a medication called acetazolamide given before surgery to see if it can help prevent shoulder pain after a laparoscopic hysterectomy. If you are a woman scheduled for this type of hysterectomy, you may be able to join.
Greenville, South CarolinaAges 21–65 - NCT07118462RecruitingPhase 4
Acetazolamide, high altitude, and plasma volume study
This trial tests how acetazolamide affects your body's fluid levels at high altitude. It might help understand if the drug can prevent altitude sickness.
BishkekAges 18–44 - NCT07199088Recruiting
Comparing two medicines for fluid buildup in heart failure
This study tests whether adding acetazolamide or metolazone to standard treatment helps remove extra fluid better in people hospitalized for heart failure. It aims to find a safer and more effective option for managing fluid overload.
Chak Four Hundred Fifty-four, Punjab ProvinceAges 18 years+ - NCT02703220RecruitingPhase 4
Sleep apnea treatment in older adults
This study tests whether certain medications can help older adults with mild to moderate sleep apnea breathe better during sleep. It aims to improve sleep quality and safety for elderly patients.
Detroit, MichiganAges 60–89 - NCT06166654RecruitingPhase 4
Better water pill therapy for acute heart failure
This trial tests different water pill (diuretic) strategies for people hospitalized with acute heart failure and too much fluid. It is designed for patients who may not respond well to standard water pills, to find a more effective way to relieve symptoms.
Hvidovre, Capital Region of DenmarkAges 18 years+ - NCT07372040RecruitingPhase 2
Adding a Water Pill for Heart Failure in the Hospital
This trial tests if adding a diuretic (water pill) called acetazolamide to usual care can help you get rid of extra fluid faster while you are in the hospital for worsening heart failure.
TantaAges 18 years+ - NCT06414759RecruitingPhase 4
Combination diuretic therapy for heart failure fluid overload
This trial tests a combination of water pills (diuretics) to help remove extra fluid in people hospitalized with acute decompensated heart failure (sudden worsening of heart failure). It aims to find a safe and effective way to reduce swelling and fluid buildup.
Giza, GZAges 18–65 - NCT04118387RecruitingPhase 4
Study of how to treat central sleep apnea in Veterans
This Phase 4 study looks at what’s going on in the body during central sleep apnea and uses that information to guide treatment. If you have central sleep apnea, this could help confirm or improve how treatment is chosen for you.
Detroit, MichiganAges 18 years+ - NCT05293600RecruitingPhase 1/Phase 2
Rescue medicine trial for sleep apnea after other treatments fail
This trial studies a “rescue” set of medicines for obstructive sleep apnea when two common treatments haven’t worked well enough. If you still have frequent breathing pauses during sleep, the study may test whether these medicines can reduce them and improve safety and symptoms.
Boston, MassachusettsAges 21–70 - NCT05589753RecruitingPhase 1/Phase 2
Testing treatment for sleep breathing problems in people on opioids
This trial studies a treatment approach for sleep-disordered breathing (breathing problems during sleep) in Veterans who take prescription opioids. It may help doctors learn safer ways to manage sleep breathing issues that can be made worse by opioid use.
Detroit, MichiganAges 18–89 - NCT05707442RecruitingPhase 3
Stent or standard treatment for idiopathic intracranial hypertension
This Phase 3 trial compares putting in a venous sinus stent versus using medicine alone for idiopathic intracranial hypertension (IIH). It aims to see which approach better protects vision and lowers pressure in the brain.
Beijing, Beijing MunicipalityAges 18–60
What Acetazolamide is being studied for
Conditions with recruiting Acetazolamide studies.
Common questions
- Are there clinical trials studying Acetazolamide?
- Yes. Clin2 currently lists 25 recruiting studies that include Acetazolamide, drawn from the U.S. registry and rewritten for real people so you can see what each is testing and who it's for.
- How do I know if I qualify for a Acetazolamide trial?
- Each study lists its own eligibility criteria — rules about condition, age, and prior treatments. On every Clin2 trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Is Acetazolamide an approved treatment?
- A drug being studied in a trial may be investigational (still being tested) or already approved and being studied for a new use. Each study page explains what phase it's in. Clin2 does not provide medical advice — talk with your doctor about whether Acetazolamide or a specific trial is right for you.
Related treatments
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. A drug appearing here is being studied in a trial and may be investigational. Talk with your doctor about whether a specific treatment or trial is right for you.