Measuring vancomycin in spinal fluid after brain bleed surgery
Treatments studied
Part of Brain & nervous system, Heart & circulation clinical trials.
This study checks how the antibiotic vancomycin moves into the fluid around the brain and spine after surgery for a type of bleeding stroke called subarachnoid hemorrhage. It aims to find better doses to prevent infections, which could help patients recover.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You had a type of bleeding stroke called subarachnoid hemorrhage, with bleeding graded as 2, 3, or 4 on a CT scan.
- You have a small tube (called an EVD) placed in your brain to drain fluid, or you will have one placed.
- You are scheduled for or have had surgery to clip the bleeding vessel.
- You are between 18 and 80 years old.
- You are medically stable after initial treatment.
- You do not have conditions like severe bleeding disorders, kidney problems, or hearing loss that could be affected by vancomycin.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This early-stage study tests whether giving preventive (prophylactic) antibiotics helps prevent infections when an external brain fluid drain (EVD) is placed and used. It may help lower the chance of serious infections around the drain.
This study looks at patients age 18+ who need a procedure to drain brain fluid after certain brain bleeds (like intraventricular or subarachnoid bleeding, or chronic subdural bleeding) or after ventriculitis. It aims to better understand and improve care for people with these serious conditions.
This study uses special MRI scans to look at the swelling around a brain bleed. Researchers want to learn more about this swelling to help guide future treatments, and the study involves only imaging, not a new drug.
This study looks for clues in your blood or spinal fluid that might predict brain spasms, delayed damage, or infections after a brain bleed. If you already need a drain to remove fluid, you could be a candidate.
This study measures how much of the antibiotic telavancin reaches the fluid around your brain and spine when you have a drain in place. It will help doctors understand if this drug is effective for treating brain infections.
This trial tests whether draining fluid from the lower back (called lumbar drainage) early after a brain bleed in the ventricles helps improve recovery. If you've had a bleed in the ventricles, this study may help reduce complications and improve outcomes.
Hear when a new Subarachnoid Hemorrhage trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.