Preventing EVD infections with antibiotics before device placement
Part of Brain & nervous system, Heart & circulation, Infections clinical trials.
This early-stage study tests whether giving preventive (prophylactic) antibiotics helps prevent infections when an external brain fluid drain (EVD) is placed and used. It may help lower the chance of serious infections around the drain.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older.
- You have a brain bleed (subarachnoid or intracerebral) or a sudden stroke that requires an EVD.
- If your EVD needs to be replaced, you would still continue in your assigned study antibiotic plan after the replacement.
- You have not taken antibiotics in the 7 days before being admitted.
- Your baseline white blood cell count is at least 5,000 (not too low).
- You do not have signs of meningitis, ventriculitis, or another active infection at the start of the study.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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