Stopping blood thinners after heart surgery for atrial fibrillation
Part of Heart & circulation clinical trials.
This trial tests whether it is safe for patients with atrial fibrillation to stop taking blood thinners after they have had heart surgery, including closure of the left atrial appendage. The goal is to see if these patients can avoid long-term medication without increasing the risk of stroke.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be over 18 years old.
- You must have had heart surgery at least 3 months ago, including a procedure to close the left atrial appendage.
- You must have a history of atrial fibrillation or atrial flutter (an irregular heart rhythm).
- You should currently be taking a blood thinner (warfarin or a DOAC like apixaban or rivaroxaban).
- You cannot have a mechanical heart valve or a history of blood clots like a pulmonary embolism.
- You cannot have severe kidney disease (estimated filtration rate lower than 30).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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This trial studies whether closing off part of the heart (the left atrial appendage) can prevent stroke as well as long-term newer blood-thinner pills. It may help people with atrial fibrillation who recently had a stroke or a warning stroke (TIA).
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