Guided pacing for heart failure with left bundle branch block
Part of Heart & circulation clinical trials.
This study tests a new way to place a pacemaker lead inside the heart to help it beat more effectively, aiming to improve heart function and symptoms in people with heart failure and a specific electrical problem (left bundle branch block). If you meet the criteria, this could be an option to discuss with your heart doctor.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 80 years old.
- You have a specific heart rhythm problem called left bundle branch block (LBBB), which affects the heart's electrical system.
- Your heart failure is NOT caused by blocked heart arteries (it is called non-ischemic cardiomyopathy).
- Your heart's pumping ability (ejection fraction) is 40% or less, and you have symptoms like fatigue or shortness of breath (NYHA class II to IV).
- You have been on recommended heart failure medications for at least 3 months.
- You do not have persistent atrial fibrillation (a long-lasting irregular heartbeat) or a history of certain other heart rhythm issues.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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This study tests a new way to place a pacemaker lead in the left bundle branch area of the heart. It may help people who need a pacemaker to see if this approach is safe and works well.
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This trial compares two types of heart pacing to see which improves outcomes for people with heart failure. It may help those who need pacing to better coordinate heartbeats and relieve symptoms.
This study tests a new way to pace the heart to see if it can improve how well the heart pumps. It uses a special Abbott pacemaker to pace a part of the heart called the left bundle branch and adjust the timing to match your natural heart rhythm.
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This study tests a new way to place a heart device lead to help the heart beat in sync for people with heart failure and a specific abnormal heart rhythm. The goal is to see if this method improves outcomes compared with standard treatment.
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