Testing safety of newborn stem cells for dilated cardiomyopathy in young adults and children
Part of Genetic & congenital, Heart & circulation clinical trials.
This study tests whether a single intravenous infusion of stem cells from donated newborn tissue is safe for people aged 4 to 39 with dilated cardiomyopathy (a weakened, enlarged heart). It aims to find a new option for those who haven't improved enough with standard heart failure medications.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 4 and 39 years old.
- You have been diagnosed with dilated cardiomyopathy (your heart's main pumping chamber is enlarged and weak).
- Your heart's pumping strength (ejection fraction) is 45% or less, measured in the last 6 months.
- You have tried standard heart failure medicines for at least 3 months without enough improvement.
- You have not had a heart transplant and are not currently on the waiting list for a transplant.
- You do not have an active infection, cancer (within the last 5 years), or serious kidney or liver problems.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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This trial tests whether heart muscle cells made from stem cells, injected into the heart, can improve heart function in people with heart failure and a weak heart pump. It may be an option for those who are not getting enough help from other treatments.
This trial tests whether stem cells from donated umbilical cord blood can improve heart function in people with heart failure caused by blocked arteries. You'll receive one or more infusions of these cells through a vein.
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