Clinical trials
Dilated Cardiomyopathy clinical trials
Below are recruiting dilated cardiomyopathy clinical trials, each written for real people, not researchers. We’re tracking 54 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07426419RecruitingPhase 1/Phase 2
Gene therapy for BAG3-related dilated cardiomyopathy
This trial tests a gene therapy (AFTX-201) for people with dilated cardiomyopathy caused by a BAG3 gene mutation. The therapy aims to improve heart function, and the study will check if it is safe and effective.
Miami, FloridaAges 18–70 - NCT07420907Recruiting
Tracking heart health over time
This study uses a wearable patch to monitor heart-related signs in people with heart conditions. It aims to learn more about how these conditions progress, which could help improve future care.
Chicago, IllinoisAges 18 years+ - NCT06902896RecruitingPhase 1/Phase 2
FAP iCDC therapy for advanced heart failure from dilated cardiomyopathy
This trial tests a new treatment called FAP iCDC for people with end-stage dilated cardiomyopathy, a type of heart muscle disease. It aims to see if this therapy is safe and helps improve heart function when standard medicines are no longer enough.
Hangzhou, ZhejiangAges 18–75 - NCT04990297Recruiting
MRI test to better predict risk in dilated heart muscle
This trial uses a heart MRI to measure details in people with dilated cardiomyopathy and reduced pumping strength. It aims to use these MRI findings to better predict your future heart risk and guide care.
Beijing, Beijing MunicipalityAges Any age - NCT06091475Recruiting
Maintaining remission in improved dilated cardiomyopathy
This study tests whether people with dilated cardiomyopathy whose heart function has already recovered to normal can safely stop or reduce one of their heart medications while staying in remission. It aims to find the best way to keep the heart healthy without extra medicines.
LondonAges 18–85 - NCT06741995Recruiting
Testing antibodies to predict heart muscle disease progression
This study looks at whether certain antibodies (proteins in your blood) can help predict how dilated cardiomyopathy will progress. By testing your blood, researchers hope to learn more about your condition and find better ways to manage it.
Wuhan, HubeiAges 18–75 - NCT07137338RecruitingPhase 1
Gene therapy for BAG3-related dilated cardiomyopathy
This trial tests a one-time gene therapy called RP-A701 for people with dilated cardiomyopathy caused by a BAG3 gene mutation. The goal is to see if it is safe and can improve heart function.
San Diego, CaliforniaAges 18–65 - NCT07241104RecruitingPhase 1
Study of AZD4063 for PLN R14del dilated cardiomyopathy
This trial tests a new drug called AZD4063 for people with dilated cardiomyopathy caused by a specific genetic change (PLN R14del mutation). The goal is to see if the drug can improve heart function, and it requires participants to have an ICD or CRT-D device.
AmsterdamAges 18–80 - NCT07516288RecruitingPhase 1
Second CAR-DC Cell Infusion for Advanced Heart Failure
This trial tests a second dose of specialized immune cells (called CAR-DC) in patients with severe dilated cardiomyopathy (a weakened heart muscle) who received one dose before but saw their heart function decline back to baseline. The goal is to see if a second dose is safe and can improve heart function when the first treatment's benefits wore off.
Hangzhou, Zhejiang / 浙江Ages 18–75 - NCT07293338Recruiting
Heart muscle blood flow study for dilated cardiomyopathy
This study looks at how small blood vessels in the heart affect outcomes in people with dilated cardiomyopathy (an enlarged, weak heart). You may qualify if you have heart failure with a weak pump and no significant blockages in your main heart arteries.
Hangzhou, ZhejiangAges 18 years+ - NCT02432092Recruiting
Genetic testing for heart muscle disease in children and families
This study looks at genetic (DNA) changes that may cause cardiomyopathy, a disease where the heart muscle is weakened. It may help families understand possible causes and inform future care.
Indianapolis, IndianaAges Any age - NCT02445534Recruiting
Registry for cell therapy in non-ischemic dilated heart muscle disease
This is a research registry that follows people with non-ischemic dilated cardiomyopathy (a weakened heart muscle) who are already on the right medications. It helps doctors better understand how cell-based therapy and related care affect heart function over time.
LjubljanaAges 18–65 - NCT07527715Recruiting
Heart MRI Study for Dilated Heart Muscle Disease
This research uses cardiac MRI scans and patient data to better predict outcomes in people with dilated cardiomyopathy—a condition where the heart's main pumping chamber becomes enlarged and weakened. Participating could help doctors improve how they care for similar patients in the future.
Jinan, ShandongAges 18 years+ - NCT06464588RecruitingPhase 1
Testing safety of newborn stem cells for dilated cardiomyopathy in young adults and children
This study tests whether a single intravenous infusion of stem cells from donated newborn tissue is safe for people aged 4 to 39 with dilated cardiomyopathy (a weakened, enlarged heart). It aims to find a new option for those who haven't improved enough with standard heart failure medications.
Atlanta, GeorgiaAges 4–40 - NCT03527342Enrolling by invitation
Sahlgrenska heart muscle disease study
This study focuses on people with certain “heart muscle” conditions (cardiomyopathies) to better understand them and guide care. If you have one of these specific diagnoses and are an adult, you may be able to take part.
GothenburgAges 18–99 - NCT07210723RecruitingPhase 2/Phase 3
Study of danicamtiv for genetic and familial dilated cardiomyopathy
This trial tests if danicamtiv can improve heart function in people with dilated cardiomyopathy caused by certain genetic changes. It may help those who have stable symptoms but still need more treatment options.
Birmingham, AlabamaAges 18 years+ - NCT05750147Recruiting
Study for cardiomyopathy linked to family or genes
This study looks at people with cardiomyopathy (or related heart muscle conditions) and those who may be at risk because of family history or genetic test results. It may help researchers better understand who is likely to develop the condition and how best to monitor or support them.
LondonAges Any age - NCT06607471Recruiting
Study on non-ischemic heart muscle diseases
This study looks at different types of heart muscle diseases that are not caused by blocked arteries (non-ischemic cardiomyopathies). It aims to better understand how to diagnose, predict outcomes, and treat these conditions by gathering information from many patients over time.
Milan, MilanoAges 18 years+ - NCT07218887RecruitingPhase 1/Phase 2
Gene therapy for BAG3-related heart failure
This study tests an experimental gene therapy called ALXN2350 for people with dilated cardiomyopathy caused by a specific genetic change in the BAG3 gene. It aims to see if the therapy can improve heart function and slow disease progression.
Birmingham, AlabamaAges 18–70 - NCT04558723Recruiting
MRI-guided heart defibrillator placement for non-ischemic weakened hearts
This study looks at whether using a heart MRI (CMR) to guide where to place an implanted defibrillator (ICD) improves outcomes for people with a weakened heart muscle caused by non-ischemic dilated cardiomyopathy. It’s for adults who have low pumping strength and evidence of heart scarring on MRI.
Lübeck, Schleswig-HolsteinAges 18 years+ - NCT04476901RecruitingPhase 2
Study of donor stem cell treatment for non-ischemic heart failure
This Phase 2 trial tests whether donor “MSC” cells can improve heart function in people with non-ischemic dilated cardiomyopathy and reduced pumping strength. You may be eligible if your condition is already treated with standard heart medicines and you can safely undergo a heart catheterization and follow-up testing.
Stanford, CaliforniaAges 18–80 - NCT06730464Recruiting
Predicting dangerous heart rhythms in non-ischemic heart disease
This study uses heart MRI scans to predict who might develop dangerous heart rhythms. It's for people with certain types of non-ischemic heart disease who have already had an MRI with contrast.
Milan, ItalyAges 18 years+ - NCT06922851Recruiting
Protein filter therapy for dilated cardiomyopathy
This trial tests a protein filtering treatment (immunoadsorption) for people with dilated cardiomyopathy who have a specific antibody linked to heart damage. It aims to see if removing these antibodies can improve heart function.
Wuhan, HubeiAges 18–75 - NCT03479580Recruiting
Registry for coronary and small-vessel heart disease in cardiomyopathy
This study enrolls people with certain types of heart muscle diseases to learn how blocked heart arteries and tiny blood vessels affect symptoms and outcomes. It may help researchers better understand these conditions and improve future care.
La TroncheAges 18–100
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Common questions
- Are there clinical trials for dilated cardiomyopathy?
- Yes. Clin2 currently lists 54 recruiting dilated cardiomyopathy studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a dilated cardiomyopathy trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a dilated cardiomyopathy trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.