Safety of deep brain stimulation for Parkinson's disease
Part of Brain & nervous system clinical trials.
This trial tests the safety of a deep brain stimulation device for people with Parkinson's disease whose symptoms are not well controlled by medication alone. If you have had Parkinson's for at least 5 years and still experience significant ups and downs in movement despite medication, this study may be relevant for you.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 70 years old and have been diagnosed with Parkinson's disease.
- You've had Parkinson's for at least 5 years.
- Your Parkinson's symptoms are not well controlled when you're off medication (Hoehn-Yahr stage 2 or higher).
- Your movement score (UPDRS part III) is at least 30 when you haven't taken medication.
- Your symptoms improve by at least 30% after taking a standard dose of levodopa (like Madopar).
- You have at least 6 hours a day of 'off' time (when medication doesn't work) or have motor fluctuations that medication adjustments can't fix.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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