Early bone marrow transplant for severe aplastic anemia
Part of Blood & lymphatic clinical trials.
This trial tests whether an early bone marrow transplant from a half-matched family member or an unrelated donor can help people with severe aplastic anemia. It aims to restore the body's ability to make healthy blood cells.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 3 to 75 years old.
- You have severe aplastic anemia (your bone marrow is not making enough blood cells).
- You do NOT have a brother or sister who is a perfect bone marrow match.
- You have NOT had a stem cell transplant before.
- You have NOT been treated for cancer (other than skin cancer) in the last 5 years.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This Phase 2 study tests a bone marrow transplant from a closely matched related donor, plus medicine after the transplant to help prevent immune complications. It may be an option if you have severe aplastic anemia and meet specific health and lab requirements.
This trial tests whether giving children with aplastic anemia a transplant using a matched unrelated donor (a bone marrow donor who is not a family member) can help treat their condition. It aims to see if this approach is effective and safe for children who qualify.
This trial tests a new way to treat severe aplastic anemia by combining a stem cell transplant from a half-matched donor with special stem cells from umbilical cord blood. The goal is to help your body make healthy blood cells again.
This trial tests a new way to prepare the body for a donor stem cell transplant (allogeneic transplant) in people with severe aplastic anemia or other blood diseases. The goal is to make the transplant safer and more effective.
This study tests a special cord blood transplant that may help your body start making blood cells faster than a regular transplant. It is for people with severe aplastic anemia or related bone marrow failure who have not gotten better with other treatments.
This trial tests a stem cell transplant using a milder conditioning regimen and a drug called post-transplant cyclophosphamide to treat severe aplastic anemia and other acquired bone marrow failure conditions. The goal is to help patients achieve a functioning donor bone marrow with fewer side effects.
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