Vericiguat for cognitive health in heart failure
Treatments studied
Part of Heart & circulation, Mental health clinical trials.
This study tests whether the heart failure medication vericiguat can also improve thinking and memory in people with heart failure who have mild cognitive problems. It involves taking vericiguat pills and having brain scans to track changes.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are an adult (18 years or older).
- You have had heart failure for at least 6 months.
- You have mild-to-moderate memory or thinking problems (such as a MoCA score between 10 and 25).
- You can take vericiguat (not using long-acting nitrates, riociguat, or PDE-5 inhibitors like sildenafil).
- You are not pregnant or breastfeeding.
- You are able to have an MRI scan and do not have an incompatible heart device (like an old ICD or CRT) or certain heart rhythm problems.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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