Discogen study for lower back pain with leg pain
Part of Bones, joints & muscles clinical trials.
This trial tests a treatment called Discogen for people with lower back pain that also causes leg pain. It aims to see if the treatment helps reduce pain and improve function.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 21 to 75 years old.
- You have had leg pain that shoots down one leg for more than a month.
- Your leg pain has been a 4 to 9 out of 10 in the last month.
- You have not had an epidural steroid injection in your lower back in the last 3 months.
- An MRI shows a disc problem at L3-4, L4-5, or L5-S1 with mild to moderate narrowing.
- You have no severe back problems, no previous back surgery at that level, and no metal implants in your spine.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests a new device (Disc Care) implanted during surgery to repair a herniated disc in the lower back. It is designed to reduce the chance of the hernia coming back.
This trial tests an injection of a protein called rhGDF-6 that may help repair damaged spinal discs and reduce low back pain. If you have chronic back pain from one or two degenerated discs, this treatment might be an option if other treatments haven't helped enough.
This trial tests an investigational gene therapy injected into the spine for people with long-term low back pain caused by degenerative disc disease. It aims to see if the treatment is safe and tolerable, and whether it can reduce pain and improve function.
This trial is testing a treatment approach for people with long-lasting, painful worn-out discs in the lower back (and sometimes leg pain). It looks for people who tried common non-surgical options without enough relief and who may be headed toward a lumbar procedure.
This trial tests a gel (HYDRAFIL-D) injected into painful discs in your lower back to see if it relieves pain. It's for people whose back pain hasn't improved with other treatments.
This trial tests whether your own disc cells (nucleus pulposus cells) can help heal a herniated disc and reduce pain. It is for people who have had low back pain for more than six weeks and are scheduled for disc surgery.
Hear when a new Disc Herniation trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.