Comparing two chemo regimens for stem cell transplant in T-ALL
Part of Blood & lymphatic, Cancer, Immune system & allergy clinical trials.
This trial tests which chemotherapy combination (BuCy or TBICy) works better for people with T-cell acute lymphoblastic leukemia getting their first stem cell transplant. The goal is to find the safer and more effective approach.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have T-cell acute lymphoblastic leukemia (T-ALL).
- You are between 2 and 55 years old.
- This is your first stem cell transplant.
- You are well enough to get out of bed and take care of yourself (ECOG score 0-3).
- You agree to follow the study rules and come for check-ups.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This clinical trial tests a new combination of chemotherapy drugs (called TmBU) before a stem cell transplant for people with high-risk or relapsed acute leukemia. The goal is to see if this conditioning regimen works better and is safe for patients who need a transplant.
This study compares two types of stem cell transplants for adults with T-ALL: one using a half-matched donor alone, and one using a half-matched donor plus umbilical cord blood. The goal is to see which approach gives better results with fewer side effects.
This trial tests a combination of total body irradiation and two chemotherapy drugs as preparation for a second stem cell transplant in people with blood cancers that relapsed or didn't respond to the first transplant.
This trial tests a treatment plan that uses blinatumomab (a drug that helps your immune system attack leukemia cells) combined with your own stem cell transplant. It is for people with B-ALL who cannot or choose not to have a transplant from another person.
This trial compares two types of stem cell transplants (one using donor cells, the other using your own cells) to see which works better for adults with a certain stage of T-cell lymphoma who have already responded well to initial chemotherapy.
This trial tests a combination of drugs (thiotepa, cyclophosphamide, clarithromycin, and cytarabine) before a stem cell transplant. It is for people with certain types of blood cancer who have responded well to earlier treatment.
Hear when a new Allogeneic Hematopoietic Stem Cell Transplantation trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.