Cooling treatment for newborns with brain injury from low oxygen

This trial studies whether cooling a newborn's body after a difficult birth helps prevent brain damage. Researchers will track babies treated with this cooling therapy and use brain imaging to see how well it works.

This trial tests if giving caffeine to newborns who had low oxygen at birth can help protect their brains. It compares caffeine plus standard care to placebo plus standard care for moderate to severe hypoxic ischemic encephalopathy (HIE).

This trial tests if adding a heart medication called dobutamine to standard cooling therapy helps newborns with HIE (brain injury from lack of oxygen at birth). It aims to protect the heart and brain during treatment.

This study compares different approaches to “cooling” treatment in newborns with mild hypoxic-ischemic encephalopathy (mild brain injury from not enough oxygen around birth). The goal is to see which approach works best and is safest for babies like yours.

This trial studies outcomes in newborns who had breathing problems from low oxygen before or during birth and were treated with a cooling therapy (therapeutic hypothermia). It may help doctors understand which babies benefit most and what recovery looks like over time.

This Phase 3 study tests whether cooling a newborn’s body can help babies with mild brain injury after a difficult birth. It aims to see if cooling improves brain-related outcomes compared with standard care.