Caffeine for newborn brain injury after oxygen loss
Treatments studied
Part of Brain & nervous system, Heart & circulation clinical trials.
This trial tests if giving caffeine to newborns who had low oxygen at birth can help protect their brains. It compares caffeine plus standard care to placebo plus standard care for moderate to severe hypoxic ischemic encephalopathy (HIE).
Summary written for real people, not researchers, by Clin2.
Who can take part
- Your baby must be born at 36 weeks or later (full-term).
- Your baby must weigh at least 1800 grams (about 4 pounds) at birth.
- Your baby must have severe or moderate acidosis (high acid levels in the blood) within the first hour after birth.
- Your baby must show signs of moderate to severe brain injury (like low muscle tone, poor reflexes, or seizures) in the first 6 hours.
- Your baby cannot have already received cooling therapy, caffeine, or been part of another trial that would interfere.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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