Clin2
NCT06697314Possibly a fitRecruiting

Clot removal for acute pulmonary embolism with heart strain

Acute Pulmonary Embolism (PE)Pulmonary Embolism

Part of Heart & circulation, Lungs & breathing clinical trials.

This study tests a new device (AlphaVac) that removes blood clots from the lungs using a thin tube inserted through a vein. It may be an option for people with acute pulmonary embolism who have signs of heart strain or low blood pressure.

Summary written for real people, not researchers, by Clin2.

Phase
N/A
Enrollment
256 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You have a new blood clot in your lung (acute pulmonary embolism) diagnosed within the last 14 days.
  • The CT scan shows strain on your heart (right ventricle larger than left).
  • A blood test shows a high troponin level, indicating heart muscle stress.
  • You are 18 years or older and have at least one sign of a more severe clot (like low blood pressure, fast heart rate, low oxygen, or a history of heart failure).
  • You are not pregnant, do not have a bleeding disorder, and are not on long-term blood thinners that would prevent this procedure.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT05821426Not yet recruiting
Clot removal device for recent pulmonary embolism

This trial tests a device that removes blood clots from the lungs in people with a recent pulmonary embolism. It may help improve blood flow and reduce strain on the heart.

NCT05591118Recruiting· Phase 3
Catheter treatment to remove blood clots in the lungs

This Phase 3 trial tests a catheter-based procedure to remove a lung blood clot (pulmonary embolism) and reduce strain on the heart. It may help people who have specific CT scan signs of right-heart strain.

Birmingham, Alabama
NCT05273762Recruiting
Removing blood clots from the lungs with a catheter

This trial tests a device called the FlowTriever to remove blood clots from the lungs in people with a pulmonary embolism that is not too severe. The goal is to see if this treatment can help improve heart function and symptoms without major surgery.

Mount Kisco, New York
NCT06453876Recruiting· Phase 3
Comparing clot removal, low-dose clot dissolver, and heparin for high-risk lung clot

This trial compares three treatments for an intermediate-high risk pulmonary embolism: a minimally invasive clot removal procedure (embolectomy), a low-dose clot-dissolving medication, or standard blood thinning (heparin). The goal is to see which approach works best to prevent worsening while reducing bleeding risks.

Copenhagen
NCT06143969Recruiting
Ultrasound-guided clot-dissolving treatment for intermediate-high risk pulmonary embolism

This trial tests a treatment that uses ultrasound to guide a thin tube (catheter) to deliver clot-busting medicine directly into the blood clot in your lung. It may be an option for people whose clot is serious but not yet causing shock, and who have symptoms that started within the last two weeks.

Milan, Italia
NCT07603700Not yet recruiting
Comparing treatments for a serious type of blood clot in the lungs

This study compares different real-world treatments for a serious but stable type of blood clot in the lungs (called intermediate-high risk pulmonary embolism). It aims to see which treatments work best in everyday patients, including those with other health conditions.

Nanjing, Jiangsu

Hear when a new Acute Pulmonary Embolism (PE) trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.