Nitric oxide to protect brain and kidneys in babies during heart surgery
Part of Genetic & congenital, Heart & circulation clinical trials.
This trial studies whether giving nitric oxide during heart-lung bypass surgery can help protect a baby’s brain and kidneys. If you qualify, the study team will check outcomes after surgery to see if benefits happen compared with usual care.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Your child is a newborn or infant under 1 year old.
- Your child has congenital heart disease and is scheduled for corrective surgery that uses cardiopulmonary bypass.
- Your child did NOT already need inhaled nitric oxide right before surgery.
- The surgery is planned, not an emergency.
- Your child does not have serious kidney disease before this surgery.
- Your child is able to complete the study’s brain/delirium assessments (English is not required if translation is available).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
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This Phase 3 study tests whether not giving nitric oxide during heart-lung bypass in newborns helps reduce the risk of acute kidney injury. It focuses on newborns having heart surgery for congenital heart disease.
This trial tests whether giving nitric oxide gas during heart surgery can help patients recover faster and need less breathing and circulation support afterward. It is for people having planned heart or aortic surgery with a heart-lung machine for the first time.
This trial tests whether inhaled nitric oxide gas can help full-term newborns who have severe breathing problems and high blood pressure in their lungs. It aims to improve oxygen levels and reduce the need for more intensive support.
This study tests whether inhaled nitric oxide—a gas that helps relax blood vessels—can prevent kidney injury in patients at high risk during heart surgery. If it works, it could reduce serious kidney complications after surgery.
This trial tests whether inhaled nitric oxide gas helps newborns with a specific type of congenital diaphragmatic hernia (a hole in the diaphragm that lets organs move into the chest) who have low oxygen and high blood pressure in their lungs.
This study looks at whether an inhaled nitric oxide generator and delivery system can help newborns with high lung blood pressure (pulmonary hypertension). It may help improve oxygen levels during breathing support, but it requires specific medical eligibility and informed consent.
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