Stem cell cleansing for safer transplants and boosts
Part of Blood & lymphatic, Genetic & congenital, Hormones & metabolism, Immune system & allergy, Skin clinical trials.
This trial gives patients access to a special machine that cleans stem cells before they are transplanted, which may reduce the risk of graft-versus-host disease. It is for patients getting certain types of stem cell transplants or having poor graft function after a transplant.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Patient must be older than 1 month of age.
- Patient must be getting a stem cell transplant for one of these reasons: a non-cancerous condition where severe GVHD is a risk (like sickle cell disease or immune deficiency), or a transplant using their own cells to rebuild the blood system, or they have poor graft function after a previous transplant.
- Patient must not have more than one active cancer at the time of joining.
- Patient must not have a fully matched sibling donor.
- Patient must not have active graft-versus-host disease or an uncontrolled transplant-related complication.
- Women who could become pregnant and men with partners who could become pregnant must agree to use birth control and avoid pregnancy for at least 1 year after the stem cell infusion.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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