Ketamine for stroke patients within 24 hours
Part of Brain & nervous system, Heart & circulation clinical trials.
This trial studies whether ketamine given soon after an ischemic stroke (blocked blood flow) can reduce early brain injury. It may help some people by limiting harmful brain reactions after stroke.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are age 18 or older with an ischemic stroke that started within 24 hours
- Your MRI shows an acute stroke using specific scan results (diffusion imaging with a matching ADC finding)
- Before the stroke, you were able to function fairly well (modified Rankin score 0–2)
- You can provide consent yourself, or a legally allowed proxy can consent for you
- You are not pregnant or breastfeeding
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests a clot-busting drug for people who had a stroke more than 4.5 hours ago. It uses a special CT scan to see if the treatment can still help them.
This Phase 4 study tests whether using a specific calming medicine (dexmedetomidine) for a longer period after a successful clot-removal procedure helps people do better in the long term. It may help improve outcomes after ischemic stroke where the clot is successfully treated.
This trial tests an investigational injection called KPCXM18 for people having an acute ischemic stroke. It is given within 12 hours of symptom onset, in addition to standard clot-dissolving treatment, to see if it improves recovery and safety.
This trial tests if ketamine can help stop seizures that haven't responded to standard medicines. It is for adults whose seizures continue after two or more emergency treatments.
This trial tests whether a single dose of ketamine can quickly improve depression by studying brain chemical changes using MRI. It's for people with treatment-resistant depression who haven't used ketamine before.
This Phase 4 trial tests whether giving ketamine during anesthesia is safe and helpful for adults with severe sudden brain injuries after surgery. It may improve how patients are sedated and cared for while they are on a breathing machine.
Hear when a new Acute Ischemic Stroke trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.