Depression treatment based on your brain's activity
Part of Mental health clinical trials.
This study tests a personalized treatment for depression that uses your brain's electrical activity (EEG) to guide therapy. You attend sessions where we monitor your brain's response to help improve your mood.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have major depression and score above 14 on a depression scale at two visits one week apart.
- Your antidepressant medication (if any) has been the same dose for at least 3 months and stays stable during the study.
- You are between 18 and 65 years old.
- You speak Hebrew fluently.
- You are not currently in psychotherapy.
- You do not have suicidal thoughts, substance abuse, schizophrenia, bipolar disorder, severe eating disorder, or organic brain disease.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study tests a structured talk-therapy program (supportive-expressive and emotion-focused therapy) for people with major depression. It may help by teaching new ways to understand and work with emotions as part of treatment.
This study is testing whether measuring your brain's electrical activity (EEG) during MRI can help personalize a type of brain stimulation treatment called TMS (transcranial magnetic stimulation) for people with hard-to-treat depression. The goal is to find early markers that predict who will respond to this treatment, so it can be tailored to each person for better results.
This trial studies whether a personalized combination of talk therapy (CBT) and antidepressant medication works better for people with moderate to severe depression. It’s meant to match treatment choices to your situation and to see what helps most.
This trial studies a way to change how excitable the brain is (through in-person brain stimulation) in people with major depression. It may help understand new treatments or symptom patterns that could be useful for major depression.
This study tests if a type of brain stimulation (TMS) can improve brain function in people with depression. It also includes a small group of epilepsy patients who are already having brain monitoring. The goal is to find new ways to treat depression by targeting specific brain areas.
This study uses brain-signal targeting (likely with MRI) to see whether it can improve certain symptoms of depression. You may be able to join if you’re 18–65 and currently have a depressive episode, and if you can safely complete the scan.
Hear when a new Major Depressive Disorder trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.