Clin2
NCT06756828Possibly a fitNot yet recruiting

Melatonin for memory loss in Alzheimer's disease

ElderlyAlzheimer DiseaseMelatoninCognitive DeclineBiomarker with Neurodegeneration PatientsCerebellum

Treatments studied

Part of Brain & nervous system, Mental health clinical trials.

This study tests whether taking melatonin for 3 months can slow down memory loss and protect the brain in people with early Alzheimer's disease. Melatonin is a natural hormone that helps regulate sleep, and it may also have protective effects on the brain.

Summary written for real people, not researchers, by Clin2.

Phase
N/A
Enrollment
40 people
Ages
60 years to 90 years
Study type
Interventional

Who can take part

  • You must be between 60 and 90 years old.
  • You must have memory or thinking problems that you have talked to a doctor about.
  • You need to be able to have brain scans like MRI and PET scans.
  • You should be able to do memory tests and physical tests at the hospital.
  • If you take memory medications, you must have been on the same dose for at least 3 months (or 1 month for other meds).
  • You cannot be taking sleeping pills in the 2 weeks before the study starts.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT03954899Recruiting
Melatonin test for brain health in older adults

This study tests whether taking 5 mg of melatonin can improve thinking and brain health over time in older adults with early, mild symptoms. You may help researchers learn which brain changes and measures improve with melatonin.

Iowa City, Iowa
NCT07172815Not yet recruiting· Phase 2
Tadalafil for early Alzheimer's and memory loss

This study tests whether a daily pill (tadalafil, a type of medicine usually used for blood pressure or erectile dysfunction) can help people with early Alzheimer's or mild memory problems. It aims to see if this drug can improve memory and slow down the disease, with the help of regular checkups and brain scans.

NCT05776641Recruiting
Light and sound training to help prevent Alzheimer’s memory loss

This study tests whether regular “gamma” light and sound stimulation can delay or prevent Alzheimer’s disease-related memory decline in people who are currently not showing dementia but are at higher risk. It uses brain testing (MRI and PET) and memory/language tests over about 13 months.

Boston, Massachusetts
NCT06619613Recruiting· Phase 1
Study of CM383 for early Alzheimer's disease

This trial tests a new drug called CM383 in people with mild cognitive impairment or mild Alzheimer's disease. The goal is to see if it can help slow down memory loss.

Hefei
NCT04570085Recruiting· Phase 3
Caffeine treatment to improve thinking in Alzheimer’s disease

This trial tests whether changing caffeine intake can improve thinking and brain function in people with Alzheimer’s disease. You may qualify if you can follow a low-caffeine diet and have stable Alzheimer’s treatment and sleep/heart conditions.

Amiens
NCT07226674Recruiting
Study of gut health and plant nutrients for brain health

This trial tests whether a natural plant compound can help support memory and thinking in people at higher risk for Alzheimer's disease. You may qualify if you are over 50, overweight, eat a typical Western diet, and have a family history of Alzheimer's.

Coleraine

Hear when a new Elderly trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.