Clinical trials
Lidocaine Infusion clinical trials
Below are recruiting lidocaine infusion clinical trials, each written for real people, not researchers. We’re tracking 30 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06427707RecruitingPhase 2/Phase 3
Adding propofol or ketamine to magnesium and lidocaine for nasal surgery
This trial tests whether adding propofol or ketamine to a standard combination of magnesium and lidocaine improves pain control and recovery for people having nasal surgery. It aims to find a better way to manage anesthesia and reduce side effects.
Cairo, Cairo GovernorateAges 18–60 - NCT06785987Enrolling by invitationPhase 4
Lidocaine Drip During Thyroid Surgery with Nerve Monitoring
This study tests whether giving a continuous lidocaine drip during open thyroid surgery can improve pain control and recovery. Lidocaine is a numbing medicine, and researchers want to see if it helps without interfering with the nerve monitor used during surgery.
Kaohsiung, TaiwanAges 20–75 - NCT07555314Recruiting
Outpatient Catheter for Lidocaine Pain Treatment
This trial tests using a special catheter (thin tube) to deliver lidocaine—a numbing medication—to treat chronic pain on an outpatient basis. Researchers want to see if this approach helps manage long-term pain effectively.
WarsawAges 18 years+ - NCT07073846RecruitingPhase 4
Lidocaine and dexmedetomidine for pain after weight-loss surgery
This study tests whether adding two medicines (lidocaine and dexmedetomidine) to your anesthesia during weight-loss surgery can reduce pain, swelling, and stress on the body. It might help you have a smoother recovery.
Mexico City, Mexico CityAges 18–60 - NCT06910644Recruiting
Pain relief after mastectomy: dexmedetomidine vs lidocaine
This trial tests whether adding dexmedetomidine or lidocaine to anesthesia during mastectomy helps reduce long-term pain after surgery. It's for women with breast cancer undergoing mastectomy with lymph node removal.
CairoAges 18–75 - NCT07327905Recruiting
Lidocaine or dexmedetomidine for pain during weight-loss surgery
This trial compares two medicines given through an IV during sleeve gastrectomy (weight-loss surgery) to see which provides better pain control. It may help patients have a smoother recovery with less discomfort.
AlexandriaAges 20–50 - NCT06768580Recruiting
Melatonin or lidocaine to prevent confusion after hip replacement
This trial tests if giving either oral melatonin or lidocaine during surgery can reduce the chance of confusion (delirium) in older adults after total hip replacement. It compares these two approaches to standard care.
Tanta, El-GharbiaAges 65 years+ - NCT07062367Recruiting
Anesthesia options for laparoscopic hysterectomy and brain health
This study compares three ways to give anesthesia during laparoscopic hysterectomy: one type of gas (sevoflurane) with or without a lidocaine IV drip, versus a different IV anesthesia (propofol). The goal is to see which approach best protects pressure inside your head and oxygen levels in your brain during surgery.
Tanta, El-GharbiaAges 18–65 - NCT05885230Recruiting
Pain relief after heart surgery: nerve block vs lidocaine drip
This trial compares two ways to manage pain after open-heart surgery: an ultrasound-guided nerve block (PIFB) versus lidocaine given through a vein. The goal is to see which method works better and helps you recover more comfortably.
Banī Suwayf, e\EYGPTAges 18–75 - NCT07423650RecruitingPhase 4
Continuous Nefopam infusion after pancreas surgery
This trial tests if giving a steady dose of a painkiller called nefopam through an IV can help manage pain after a Whipple procedure (pancreatoduodenectomy). It aims to see if this approach reduces the need for other pain medications and improves recovery.
Cluj-Napoca, ClujAges 18–80 - NCT07552766RecruitingPhase 4
Lidocaine infusion to reduce opioid use in arm fracture surgery
This study tests whether giving a pain-relieving medication called lidocaine through an IV during arm fracture surgery can reduce how much opioid pain medication (like morphine) children need after surgery. The goal is to help manage pain better while using fewer opioids.
Wilmington, DelawareAges 3–18 - NCT07108764Recruiting
Medicine to prevent confusion after abdominal surgery in seniors
This trial tests giving either lidocaine or dexmedetomidine during abdominal surgery to see if it helps keep the brain healthy and lowers the chance of waking up confused or agitated. It is for older adults having planned abdominal surgery who are otherwise in fairly good health.
Tanta, El-GharbiaAges 65 years+ - NCT06710405RecruitingPhase 4
Lidocaine for pain relief after children's chest surgery
This trial tests whether giving lidocaine during surgery can reduce pain and speed up recovery in children under 7 having chest surgery with a camera. If it works, it could mean less pain and a faster return to normal after the operation.
SeoulAges 6 months–7 years - NCT07193836Enrolling by invitation
Lidocaine for easier recovery after laparoscopic surgery
This study tests whether giving lidocaine (a numbing medicine) through an IV can help you wake up more smoothly and with less discomfort after laparoscopic gallbladder or gynecologic surgery. If you are generally healthy and having one of these specific surgeries, you may be a good fit.
Yinchuan, NingxiaAges 18–70 - NCT07061847RecruitingPhase 2
Lidocaine infusion for severe chronic migraines
This trial tests if a lidocaine infusion into an artery in the head can reduce severe chronic daily headaches. It is for people who have tried multiple treatments without enough relief.
Great Neck, New YorkAges 18–75 - NCT04048278RecruitingEarly Phase 1
Lidocaine IV infusion for pancreatic cancer treatment
This early-phase study tests whether giving lidocaine through an IV infusion can help treat pancreatic cancer. It will enroll people with confirmed pancreatic cancer that can be measured on scans, including some cases discovered to have spread during surgery.
Chicago, IllinoisAges 18 years+ - NCT07488832Recruiting
Lidocaine for pain control after spine surgery
This trial tests whether giving lidocaine through an IV during surgery can help reduce pain after lumbar fusion surgery. It may lead to less need for other pain medicines and a smoother recovery.
AnkaraAges 18–65 - NCT07048769RecruitingPhase 4
Pain relief shot for saline ultrasound of the uterus
This trial tests if a numbing injection in the cervix reduces pain during a saline ultrasound that checks the uterus and fallopian tubes. It might help make the procedure more comfortable for you.
Hartsdale, New YorkAges 18–50 - NCT07408193RecruitingEarly Phase 1
Lidocaine and ketamine for severe cancer pain not helped by opioids
This trial tests if adding lidocaine and ketamine to your current pain medicines can better control severe cancer-related pain that opioids alone haven't helped.
Athens, AtticaAges 18 years+ - NCT05072314RecruitingPhase 3
Lidocaine drip after breast surgery to improve long-term pain
This Phase 3 study tests whether a long-running lidocaine (a numbing medicine) drip given around the time of breast surgery can improve long-term post-surgery pain and recovery. It may help people who have pain after mastectomy or breast-conserving surgery.
Kingswood, New South WalesAges 18 years+ - NCT04874038RecruitingPhase 3
Lidocaine infusions to prevent long-lasting pain after breast surgery
This Phase 3 study tests whether receiving lidocaine through an IV during breast surgery can lower the chance of ongoing pain afterward. If it works, it may help some people avoid chronic, surgery-related pain in the chest wall, shoulder, or arm.
Calgary, AlbertaAges 18–100 - NCT06349668RecruitingPhase 3
Comparing spinal morphine and IV lidocaine for robotic kidney surgery
This trial compares two ways to manage pain during robotic-assisted kidney or ureter surgery: a spinal injection of morphine or an intravenous infusion of lidocaine. The goal is to see which method provides better pain relief and recovery.
KalmarAges 18 years+ - NCT06582810Recruiting
Lidocaine for headaches after brain bleed
This study tests whether a lidocaine infusion (given through an IV) can safely reduce severe headaches after a subarachnoid hemorrhage (a type of brain bleed). You may qualify if you had a spontaneous bleed and can communicate your pain level.
Wichita, KansasAges 18 years+ - NCT06793527Recruiting
Pain relief methods for laparoscopic bariatric surgery
This trial compares three different pain relief methods during weight-loss surgery: a nerve block, a lidocaine drip, and a targeted injection near the celiac plexus. The goal is to find which approach works best with fewer side effects.
Krakow, Lesser Poland VoivodeshipAges 18–75
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Common questions
- Are there clinical trials for lidocaine infusion?
- Yes. Clin2 currently lists 30 recruiting lidocaine infusion studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a lidocaine infusion trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a lidocaine infusion trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.