Semaglutide after stroke clot removal for better recovery
Treatments studied
Part of Brain & nervous system, Heart & circulation clinical trials.
This trial tests whether a drug called semaglutide (usually used for diabetes) can improve brain recovery when given after a stroke clot removal procedure. You may receive the drug or a placebo, and researchers will check your neurological outcomes.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are at least 18 years old
- You have had an acute ischemic stroke (blockage in a brain blood vessel) within the last 24 hours
- Your doctor plans to remove the clot with a procedure called endovascular thrombectomy
- Before the stroke, you could manage daily activities on your own (no significant disability)
- You do not have severe bleeding in the brain, severe heart disease, or are not pregnant or breastfeeding
- You are not allergic to semaglutide, the study medication
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This Phase 2 study tests whether a semaglutide injection given under the skin soon after an acute ischemic stroke can improve recovery. It may help reduce disability, especially if treatment starts within about 4.5 hours of symptom onset.
This study tests whether a medication called a GLP-1 receptor agonist (a type of drug used for diabetes) can improve recovery after a major stroke that was treated with a procedure to remove the blood clot. The goal is to see if this drug helps reduce further brain damage and improve outcomes.
This trial tests if giving a steroid (methylprednisolone) directly into the brain artery after successful clot removal improves recovery. It is for people who had a large stroke in the front part of the brain and got the clot out within 24 hours.
This trial tests whether a medicine called an SGLT2 inhibitor, which is usually used for diabetes, can help protect the brain and improve recovery when given soon after a stroke. It is for people who had a stroke within the last 3 days and have moderate to severe symptoms.
This trial tests whether a medication commonly used for diabetes can help patients who had a stroke due to a blocked large artery in the brain. The drug is given as an injection after the standard procedure to remove the blood clot, and researchers will see if it leads to better recovery.
This trial tests whether a medicine called a GLP-1 receptor agonist (similar to diabetes drugs) can improve recovery after a specific type of bleeding stroke. The study aims to see if this drug can reduce brain swelling and help patients regain function.
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