Semaglutide for stroke recovery after clot removal
Treatments studied
Part of Brain & nervous system, Heart & circulation clinical trials.
This trial tests if semaglutide, a diabetes drug, can improve brain recovery after a stroke when given within 24 hours of symptom onset and before a clot-removal procedure. It may help reduce disability and improve neurological outcomes.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must have had a stroke caused by a blocked blood vessel in the brain, diagnosed within 24 hours.
- You must be scheduled for a procedure to remove the clot from the brain.
- You must be 18 years or older.
- Before the stroke, you were able to take care of yourself without help (score 0 or 1 on the modified Rankin Scale).
- You or your legal representative must agree to participate in the study.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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This Phase 2 study tests whether a semaglutide injection given under the skin soon after an acute ischemic stroke can improve recovery. It may help reduce disability, especially if treatment starts within about 4.5 hours of symptom onset.
This study tests a medicine (a GLP-1 receptor agonist) given along with the standard clot-removal procedure for people who have had a severe stroke from a large blockage. The goal is to see if the medicine helps improve recovery by protecting the brain.
This study tests if adding a GLP-1 receptor agonist (a type of diabetes medicine that also helps blood vessels) to standard clot removal can improve recovery after a severe stroke. It is for people who had a clot removal for a large artery blockage and can start the drug within 6 hours.
This trial tests whether semaglutide changes blood flow in the brain and the brain’s “barrier” (how well the brain is protected) in people with type 2 diabetes. It may help researchers understand brain-related effects of diabetes treatment using scans and blood tests.
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This study tests if a daily semaglutide pill can reduce harmful fat around the heart in people with type 2 diabetes who had a heart attack 2 to 9 months ago. It aims to see if this treatment can improve heart health.
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